What are the best study materials and plan for preparing for the United States Medical Licensing Examination (USMLE)?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: December 30, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

USMLE Preparation Strategy

I cannot provide evidence-based recommendations for USMLE study materials and preparation plans because the provided evidence consists entirely of guidelines for specialized medical imaging training (echocardiography, cardiovascular MRI, emergency ultrasound) and continuing medical education—none of which address USMLE preparation strategies.

What the Limited Research Shows

The available research evidence does offer some insights:

Strongest Predictor of Success

Pre-clinical academic performance is the most powerful predictor of USMLE Step 1 success (r = 0.719), far exceeding any commercial study resource 1.

Evidence-Based Study Strategies

For Step 2 CK preparation, completing a high volume of practice questions is the only study method that independently predicts higher scores after controlling for prior performance 2. Specifically:

  • Working through more case-based, clinically-focused questions correlates with better performance 2
  • The proportion of a question bank completed shows positive correlation 2

For Step 1 preparation, UWorld Qbank completion at least once shows statistically significant positive association with scores 1. However:

  • Using multiple other commercial products does not correlate with performance 1
  • Completing multiple practice exams does not show statistical significance 1
  • Longer dedicated study periods (more days) were negatively correlated with performance in one cohort 1

Program-Level Interventions

A student-initiated program providing First Aid for USMLE Step 1 early in second year plus a six-month UWorld subscription resulted in an 8.82-point average score improvement and 8% increase in first-attempt pass rates 3.

Critical Limitation

The evidence base for USMLE preparation strategies is remarkably thin, consisting of only observational studies from single institutions with small sample sizes 2, 3, 1. No high-quality guidelines or systematic reviews address optimal USMLE preparation methods.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.