Mortality in Functional Neurological Disorder
FND does not cause death or shorten lifespan—it is not a degenerative or life-threatening condition, and mortality is not elevated compared to the general population. 1
Direct Mortality Risk
- There are no recorded deaths directly attributed to FND itself, as the disorder does not cause permanent structural damage to the nervous system 2, 1
- The symptoms arise from a potentially reversible miscommunication between the brain and body, not from structural neurological disease that could be fatal 2, 3
- FND is fundamentally different from degenerative neurological conditions that can affect lifespan 2
Important Caveats: Secondary Complications
While FND itself is not fatal, certain secondary complications require clinical vigilance:
Respiratory Compromise
- Patients with functional seizures who develop potential respiratory compromise require continuous cardiorespiratory monitoring, particularly in acute presentations 2
- This represents a management consideration for the acute symptom manifestation, not mortality from FND itself 2
Nutritional Complications
- Functional dysphagia can lead to unintended weight loss, malnutrition, and social withdrawal 2
- These complications require monitoring and intervention but are preventable with appropriate management 2
Deconditioning Effects
- Prolonged immobility or reduced activity can lead to secondary problems such as deconditioning and muscle atrophy 2
- Maladaptive movement patterns can create new musculoskeletal problems including secondary pain syndromes 2
Clinical Implications
- When counseling patients, emphasize that FND symptoms are real but potentially reversible, and do not represent a life-threatening condition 2, 3
- The high levels of distress, disability, unemployment, and reduced quality of life experienced by many patients reflect the burden of symptoms and associated stigma, not a life-threatening disease process 2
- Early diagnosis and treatment are critical for optimal outcomes, with 60-96% of patients reporting improvement after intervention 1