What is the recommended dosage of Fexofenadine (Allegra) for acute sinusitis?

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From the Research

Fexofenadine is not specifically used to treat sinus infections, but rather to relieve allergy symptoms that may accompany or be confused with sinus infections, with a recommended dosage of 60 mg twice daily or 180 mg once daily for adults and children 12 years and older, as supported by the most recent study 1.

Key Points to Consider

  • Fexofenadine only treats allergy symptoms like sneezing, runny nose, and itchy eyes by blocking histamine receptors; it does not address the underlying infection.
  • A true sinus infection (sinusitis) is typically caused by bacteria or viruses and may require antibiotics if bacterial in nature.
  • If symptoms persist or worsen, medical attention is necessary to determine the underlying cause of the infection.

Important Considerations for Fexofenadine Use

  • Children 6-11 years old should take 30 mg twice daily.
  • Avoid fruit juices as they can decrease absorption, and take the medication with water.
  • Fexofenadine displays a favorable safety profile and results in greater treatment satisfaction in children compared with other second-generation antihistamines, as noted in the study 1.

When to Seek Medical Attention

  • If you have symptoms like facial pain/pressure, thick yellow/green nasal discharge, and fever lasting more than 10 days, you should consult a healthcare provider for proper diagnosis and treatment.
  • The study 2 highlights the importance of accurate diagnosis and prompt treatment to reduce costs related to unnecessary investigations, time lost from work, and complications due to inappropriate treatment.

References

Research

Fexofenadine: review of safety, efficacy and unmet needs in children with allergic rhinitis.

Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology, 2021

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Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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