Best Strategy to Improve Memory
The single most effective intervention to improve memory is structured exercise, specifically 150 minutes per week of moderate-intensity aerobic activity, with resistance training added 2-3 times weekly for optimal benefit. 1
Exercise as Primary Intervention
Aerobic exercise is the cornerstone recommendation for memory improvement, supported by the highest-quality guideline evidence. The 5th Canadian Consensus Conference on Dementia specifically recommends aerobic exercise to improve cognitive outcomes, including memory function. 1
Specific Exercise Prescription
The evidence-based dosing for memory improvement is clear and actionable:
- Minimum effective dose: 150 minutes per week of moderate-intensity aerobic activity (approximately 724 METs-min per week) 1
- Optimal dose range: 150-300 minutes per week of moderate-intensity aerobic activity 1
- Practical implementation: Start with 30 minutes of brisk walking 5 days per week, where the patient can talk but not sing during activity 1
Resistance training provides superior cognitive benefits compared to aerobic exercise alone according to the most recent 2022 network meta-analysis. 2 The WHO recommends adding muscle-strengthening activities involving major muscle groups at least three times per week. 3
Important Exercise Principles
- Benefits begin immediately with no minimal threshold required 3
- The dose-response relationship is non-linear, with diminishing returns beyond 1200 METs-min per week (300 min/week) 3
- Multicomponent exercise (combining aerobic and resistance training) is most effective for mild cognitive impairment 3
- Lower doses of resistance training can achieve clinically meaningful benefits, making high-intensity programs unnecessary for many patients 3
Cognitive Rehabilitation Strategies
Beyond exercise, structured cognitive interventions are reasonable approaches:
- Enriched environments that increase engagement with cognitive activities are recommended 2
- Cognitive rehabilitation to improve attention, memory, visual neglect, and executive functioning is reasonable 2
- Specific memory training is reasonable, such as promoting global processing in visual-spatial memory and constructing semantic frameworks for language-based memory 2
Compensatory Memory Strategies
Compensatory strategies may be considered and include: 2
- Internalized strategies: Visual imagery, semantic organization, spaced practice 2
- External memory aids: Notebooks, paging systems, computers, other prompting devices 2
- Errorless learning techniques may be effective for severe memory impairments, though benefits are limited to specific skills with minimal transfer to novel tasks 2
Additional Cognitive Interventions
- Music therapy may be reasonable for improving verbal memory 2
- Virtual reality training may be considered for verbal, visual, and spatial learning, though efficacy is not well established 2
Nutritional Considerations (Adjunctive)
While exercise remains the primary evidence-based intervention, certain dietary factors may provide supplementary benefits:
- Mediterranean diet (rich in fruits, vegetables, legumes, olive oil, regular fish consumption) has been shown to reduce incidence of mild cognitive impairment 4
- Omega-3 fatty acids (EPA and DHA supplementation at 2,200 mg/day) showed improved object-location memory recall in healthy older adults in a 26-week placebo-controlled trial 5
- Low glycemic index foods appear to improve attention and memory, while simple sugars are associated with concentration difficulties 6
Common Pitfalls to Avoid
- Do not focus exclusively on aerobic exercise while neglecting resistance training, as resistance training shows superior cognitive benefits 3
- Do not recommend only high-intensity programs, as lower doses of resistance training achieve clinically meaningful benefits 3
- Do not expect medications to be effective: The usefulness of donepezil, rivastigmine, and antidepressants in treating cognitive deficits is not well established 2
- Working memory training programs lack robust evidence for far-transfer effects to real-world memory improvement 2