What is the composition of Isolyte (Intravenous Electrolyte Solution)?

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From the Research

Composition of Isolyte

The composition of Isolyte, also known as an Intravenous Electrolyte Solution, is not directly stated in the provided studies. However, we can infer the general composition of balanced crystalloid solutions, which Isolyte is likely a part of, based on the information provided:

  • Balanced crystalloid solutions have a sodium, potassium, and chloride content closer to that of extracellular fluid 1
  • They have a composition that minimally affects acid-base equilibrium, with a strong ion difference (SID) close to that of plasma bicarbonate concentration (HCO₃-) 2
  • Examples of balanced crystalloid solutions include lactated Ringer's and Plasma-Lyte, which have a lower chloride content compared to 0.9% NaCl 1, 3

Characteristics of Balanced Crystalloid Solutions

Some key characteristics of balanced crystalloid solutions include:

  • Lower chloride content compared to 0.9% NaCl
  • Sodium, potassium, and chloride content closer to that of extracellular fluid
  • Minimal effects on acid-base equilibrium
  • Potential to reduce the risk of hyperchloremic metabolic acidosis and acute kidney injury compared to 0.9% NaCl 1, 3

References

1
Research

Balanced Crystalloid Solutions.

American journal of respiratory and critical care medicine, 2019

3
Research

Intravenous fluids: balancing solutions.

Journal of nephrology, 2017

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