From the Guidelines
Prescription treatment for canker sores should include topical corticosteroids, such as dexamethasone mouth rinse (0.1 mg/ml) or clobetasol gel/ointment (0.05%), as first-line therapy to reduce inflammation and promote healing 1. When it comes to managing canker sores, the goal is to alleviate symptoms, promote healing, and prevent recurrence.
- Topical corticosteroids, like dexamethasone mouth rinse (0.1 mg/ml) or clobetasol gel/ointment (0.05%), are recommended as first-line therapy for their anti-inflammatory properties 1.
- For severe cases, systemic corticosteroids, such as oral prednisone (30-60 mg or 1 mg/kg) for 1 week, followed by dose tapering, may be considered to quickly bring symptoms under control 1.
- Other treatment options, like coating agents, topical analgesic or anti-inflammatory agents, and alternative mouthwashes, may also be considered to manage symptoms and promote healing 1.
- It's essential to note that treatment should be individualized, and patients should be advised to use these approaches under the guidance of a healthcare professional.
- The use of sodium bicarbonate containing mouthwash, chewing gum, candy, salivary substitutes, or sialogogues may also be beneficial in preventing and treating stomatitis, including canker sores 1.
- Analgesics, such as viscous lidocaine (2%) or topical NSAIDs (e.g., amlexanox 5% oral paste), may be used to manage pain associated with canker sores 1.
From the Research
Canker Sore Prescription Treatment Options
- Amlexanox is considered an effective treatment for canker sores, with a 5% paste formulation showing significant benefits 2
- The use of Amlexanox 5% paste has been shown to:
- Reduce ulcer size
- Decrease pain duration
- Shorten healing time 2
Key Findings
- Studies suggest that Amlexanox may be the most effective overall treatment for recurrent canker sores 2