What is the recommended amount of drainage to remove from a chest tube?

Chest Tube Drainage Volume Recommendations

For initial drainage, limit removal to 10 mL/kg body weight, then clamp the drain for 1 hour to prevent re-expansion pulmonary edema; in adults and adolescents, do not drain more than 1.5 liters at one time or slow drainage to approximately 500 mL/hour. 1, 2

Initial Drainage Limits (Critical Safety Threshold)

The primary concern with rapid chest tube drainage is re-expansion pulmonary edema (RPO), which though rare in children, can be fatal. 1

Specific Volume Limits:

• Clamp the drain after removing 10 mL/kg body weight initially 1, 2
• In adults and larger adolescents: maximum 1.5 liters at one time 1, 2
• Alternative approach: slow drainage to approximately 500 mL/hour 1, 2
• After clamping, wait 1 hour before resuming drainage 1, 2

Critical Caveat:

If an air leak developed during drain insertion, clamping risks tension pneumothorax—never clamp a bubbling chest drain. 1, 2

Ongoing Drainage Management (When to Remove)

Traditional Thresholds:

The British Thoracic Society guidelines provide context-specific recommendations:

For malignant pleural effusions after pleurodesis:

• Remove drain within 12-72 hours if drainage is <250 mL/day 1
• Consider repeat pleurodesis if drainage persists >250 mL/day 1

For pediatric pleural infections:

• Remove drain based on clinical resolution rather than specific volume 1
• Drainage volume is one factor among temperature, clinical status, and imaging 1

Evidence-Based Higher Thresholds:

Recent thoracic surgery evidence demonstrates safety with more liberal removal criteria:

• Up to 300 mL/24 hours is safe with decreased drainage time and hospital stay 1, 2
• Up to 450-500 mL/day has been validated in multiple studies without increased complications 1, 2
• One randomized trial showed 400 mL/24 hours threshold allowed 58.8% of drains to be removed within 24 hours safely 3
• Another study validated 200 mL/day threshold with only 5.4% reaccumulation rate 4

Decision Algorithm for Drain Removal

Remove the chest tube when ALL of the following criteria are met:

1. No air leaks present (never remove with active bubbling) 1, 2
2. Drainage character is serous (clear/yellowish, not bloody or purulent) 5, 2
3. Volume shows decreasing trend toward <200-300 mL/24 hours 1, 5, 2
4. Lung remains fully re-expanded on chest radiograph 1
5. Clinical resolution (improved symptoms, stable vital signs) 1

Critical Pitfalls to Avoid

Abrupt cessation of drainage usually indicates obstruction (kinking or blockage), not resolution—check for obstruction by flushing with 10 mL normal saline. 1, 2

Never clamp a bubbling drain (indicating air leak), as this can cause fatal tension pneumothorax. 1, 2

If the drain is clamped and the patient develops breathlessness or chest pain, immediately unclamp and seek medical advice. 1

Character of drainage matters more than absolute volume—bloody drainage warrants more caution than serous fluid regardless of volume. 5, 2

Context-Specific Modifications

After cardiac surgery: Traditional practice removes drains at 100-200 mL/24 hours, though silicone-rubber (Blake) drains yield 71% more drainage than semirigid drains. 5

After lung surgery: Studies support removal at 200-400 mL/24 hours without increased complications, reducing hospital stay. 1, 4, 3

For empyema/infection: Clinical resolution takes precedence over specific drainage volumes. 1