Does Centurion cause Gastroesophageal Reflux Disease (GERD)?

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Does Centurion Cause GERD?

There is no evidence that "Centurion" causes GERD. The term "Centurion" does not appear in any medical literature, drug databases, or clinical guidelines as a medication, supplement, or substance known to cause gastroesophageal reflux disease.

Clarifying the Question

  • No known medication or substance called "Centurion" exists in standard pharmacological references that would be associated with GERD causation
  • If you are referring to a specific medication with a similar name, please verify the correct spelling, as this may be:
    • A brand name that varies by region
    • A misspelling of another medication
    • A supplement or over-the-counter product with regional naming

Medications That DO Cause or Worsen GERD

While "Centurion" is not recognized, several medication classes are well-documented to cause or exacerbate GERD:

  • NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) can worsen preexisting reflux and increase GERD symptoms with a relative risk of approximately 2, though they do not cause reflux in healthy subjects 1
  • Calcium channel blockers, nitrates, and progesterone can make GERD more difficult to control by affecting lower esophageal sphincter function 2
  • Medications that should be considered when GERD is difficult to manage include those used for comorbid conditions that may worsen reflux 2

What to Do If You Suspect Medication-Induced GERD

  • Review all current medications with your healthcare provider to identify potential culprits that affect esophageal motility or lower esophageal sphincter pressure 2
  • Consider discontinuing the suspected agent if drug-induced symptoms are a clinical possibility, to determine whether it might be playing a role 2
  • Address comorbid conditions such as obstructive sleep apnea that can make GERD more difficult to control 2

Next Steps

  • Verify the correct name of the medication or substance in question
  • Consult with your prescribing physician or pharmacist to review the complete medication profile
  • If you have GERD symptoms, empiric treatment with proton pump inhibitors is appropriate as first-line therapy regardless of the cause 3, 4

References

Research

[Esophageal complications of non steroidal antiinflammatory drugs].

Gastroenterologie clinique et biologique, 2004

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Gastroesophageal Reflux Disease (GERD) Management

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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