From the Guidelines
Liquid ketones are exogenous ketone supplements that can help diabetic patients following a fasting diet manage hunger and provide an alternative energy source, but they should be used with caution due to potential effects on blood sugar levels and interactions with diabetes medications. For diabetic patients, liquid ketones may offer benefits such as improved insulin sensitivity and weight management, but it is crucial to approach their use with caution. The most recent and highest quality study, 1, suggests that reducing overall carbohydrate intake can improve glycemia in individuals with diabetes, and liquid ketones may be a useful adjunct to this approach. However, diabetic patients should exercise extreme caution when using these supplements, as they can affect blood sugar levels and may interfere with diabetes medications.
- The typical dosage ranges from 5-15ml of liquid ketone supplements, depending on the product concentration, but this should be determined with medical supervision.
- Diabetic patients should always consult their healthcare provider before starting any ketone supplements, monitor blood glucose levels closely when using them, and understand that these supplements are not FDA-approved treatments for diabetes.
- While some research suggests potential benefits for metabolic health, liquid ketones should complement, not replace, proper diabetes management strategies including medication, diet, and regular monitoring.
- It is also important to note that the use of liquid ketones may require adjustments to insulin dosing and carbohydrate intake, and patients should work closely with their healthcare provider to determine the best approach for their individual needs, as suggested by 1.
From the Research
Definition of Liquid Ketones
- Liquid ketones refer to a type of exogenous ketone supplement that can be ingested to increase blood ketone levels.
- These supplements are often used by individuals following a ketogenic diet or by those who want to experience the benefits of ketosis without restricting their carbohydrate intake.
Effect of Liquid Ketones on Diabetic Patients Following a Fasting Diet
- According to a study published in 2024 2, acute ingestion of exogenous ketone monoester supplement did not lower blood glucose in individuals with type 2 diabetes.
- The same study found that 14-day thrice daily premeal exogenous ketone monoester supplementation also did not improve glycemic control in adults with type 2 diabetes.
- However, other studies have shown that intermittent fasting, which can induce ketosis, may have beneficial effects on glycemic control in patients with diabetes 3, 4, 5, 6.
- It is essential to note that the effects of liquid ketones on diabetic patients following a fasting diet may vary depending on individual factors, such as the type and duration of fasting, the dose and type of ketone supplement, and the individual's overall health status.
Safety and Efficacy of Intermittent Fasting for Diabetic Patients
- Studies have shown that intermittent fasting can be safely undertaken in patients with diabetes when done under the supervision of a healthcare provider and with appropriate glucose monitoring 3, 4, 5, 6.
- However, more research is needed to determine the long-term effects of intermittent fasting on diabetic patients and to establish clear guidelines for its use in this population.