Does Robaxin (Methocarbamol) lower blood pressure (hypotension)?

From the FDA Drug Label

Adverse reactions reported coincident with the administration of methocarbamol include: ... Cardiovascular system: ... hypotension, ... OVERDOSAGE ... Overdose of methocarbamol ... includes the following symptoms: ... hypotension, ...

Hypotension is listed as a possible adverse reaction and symptom of overdose of methocarbamol.

• This suggests that methocarbamol (Robaxin) may lower blood pressure in some individuals. 1 1

From the Research

Robaxin (methocarbamol) does not typically lower blood pressure as its primary effect. It is a muscle relaxant that works by affecting the central nervous system to relieve pain and discomfort caused by muscle injuries and spasms. While some muscle relaxants can cause a slight decrease in blood pressure as a side effect, this is not a common or significant effect of Robaxin. In fact, if a patient experiences a notable drop in blood pressure while taking Robaxin, it should be reported to a healthcare provider as it may indicate an adverse reaction. Robaxin works primarily by inhibiting nerve impulses or pain sensations that are sent to the brain, rather than directly affecting the cardiovascular system.

The provided evidence does not directly address the effect of Robaxin on blood pressure, but it discusses various antihypertensive medications and their effects on blood pressure. For example, a study published in 2023 2 found that non-atenolol β-blockers are effective in lowering blood pressure as add-on to monotherapy or as a component of combination antihypertensive therapy. However, this study does not mention Robaxin.

If you're looking for medication to lower blood pressure, you should consult with your healthcare provider about appropriate antihypertensive medications specifically designed for that purpose, such as:

• ACE inhibitors
• Beta-blockers
• Calcium channel blockers
• Diuretics

It's essential to note that the choice of antihypertensive medication depends on various factors, including the patient's age, medical history, and other health conditions. A healthcare provider can help determine the best course of treatment for individual patients.