What is included in a Comprehensive Metabolic Panel (CMP)?

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Last updated: April 10, 2025View editorial policy

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From the Guidelines

A Comprehensive Metabolic Panel (CMP) includes measurements of glucose, electrolytes, kidney function tests, liver function tests, and proteins, and according to the study 1, a CMP also includes phosphate. The components of a CMP can be broken down into several categories, including:

  • Glucose measurement to screen for diabetes
  • Electrolytes (sodium, potassium, chloride, carbon dioxide/bicarbonate) to assess fluid and electrolyte balance
  • Kidney function tests (BUN/blood urea nitrogen and creatinine) to evaluate how well the kidneys filter waste
  • Liver function tests (ALT, AST, alkaline phosphatase, and bilirubin) to check liver health and function
  • Proteins (albumin and total protein) to assess nutritional status and liver function
  • Phosphate levels, as indicated in the study 1, which is essential for various bodily functions, including bone health and energy production.

The study 1 mentions that a CMP is part of the clinical monitoring for patients with tyrosinemia type I, and it is essential to include phosphate in the panel to ensure comprehensive evaluation of the patient's metabolic status. The CMP provides a broad overview of metabolic and chemical balance in the body, and its components can help identify potential issues with organ function, allowing for early intervention and treatment.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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