From the Research
Number of Puffs in a Standard Inhaler
- The number of puffs in a standard inhaler can vary depending on the specific device and medication being used 1.
- According to a survey of albuterol administration practices in intubated patients in the neonatal intensive care unit, the average dose via MDI was: 1 puff: 30%; 2 puffs: 65%; and 4 puffs: 5% 1.
- The maximum dose via MDI was: 2 puffs: 30%; 3 puffs: 14%; 4 puffs: 36%; 6 puffs: 11%; and 8 puffs: 6% 1.
- In a study comparing the efficacy and safety of albuterol delivered by metered-dose inhaler (MDI), MDI with spacer, and Rotahaler device, albuterol was administered at the maximum recommended dosages of two puffs for MDI 2.
- Another study found that during nocturnal asthma, the median dose required to achieve 80% of the subject's personal best FEV(1) was substantially higher at night (5 1, 19 vs 0.4 [<0.25,2] puffs) 3.
Factors Affecting the Number of Puffs
- The choice of metered-dose inhaler (MDI) or nebulizer can affect the number of puffs required 4, 1.
- The use of a holding chamber can also impact the number of puffs needed 1.
- The time between MDI actuations and the placement location of the holding chamber or nebulizer can also influence the number of puffs required 1.