How do you treat epistaxis?

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Epistaxis Management

For active epistaxis, immediately apply firm, sustained compression to the soft lower third of the nose for a full 10-15 minutes without checking if bleeding has stopped—this single intervention resolves the vast majority of cases. 1, 2

Immediate First-Line Management

Patient Positioning and Compression

  • Position the patient sitting upright with head tilted slightly forward (not backward) to prevent blood from flowing into the airway or stomach 3, 2, 4
  • Apply firm, continuous pressure to the soft lower third of the nose (not the nasal bridge) for a minimum of 10-15 minutes without interruption 1, 3, 2
  • The patient should breathe through their mouth and spit out blood rather than swallowing it 3, 2
  • Compression alone resolves the vast majority of anterior epistaxis cases 1, 2

Common Pitfall: Most treatment failures occur because compression time is insufficient or the wrong location is compressed—only 30% of healthcare providers correctly identify the proper compression site 5

Topical Vasoconstrictors (If Compression Fails)

  • After 10-15 minutes of compression, if bleeding persists, clear clots from the nose and apply topical vasoconstrictor spray (oxymetazoline or phenylephrine)—2 sprays into the bleeding nostril 1, 3, 2
  • Resume firm compression for another 5-10 minutes after applying the vasoconstrictor 3, 2
  • Vasoconstrictors resolve 65-75% of epistaxis cases in emergency departments 2, 6
  • Caution: Vasoconstrictors may cause cardiac or systemic complications in susceptible patients 2

Advanced Interventions When Basic Measures Fail

Nasal Cauterization

  • If an anterior bleeding site is identified, electrocautery is more effective than chemical cauterization with fewer recurrences (14.5% vs 35.1%) 2, 6
  • Silver nitrate cautery can be applied to localized bleeding sites or prominent vessels 7
  • Nasal endoscopy localizes the bleeding site in 87-93% of cases 2

Nasal Packing

  • Indicated when bleeding continues despite 15-30 minutes of proper compression with vasoconstrictors, for life-threatening bleeding, or when a posterior bleeding source is suspected 1, 2
  • For patients on anticoagulants or antiplatelet medications: Use only resorbable/absorbable packing materials (Nasopore, Surgicel, Floseal) to reduce trauma during removal 1, 2, 4
  • For patients without bleeding risk factors, either resorbable or non-resorbable materials may be used 2
  • Newer hemostatic materials (hemostatic gauzes, thrombin matrix, gelatin sponge, fibrin glue) are more effective with fewer complications than traditional packing 6

Critical Medication Management

Anticoagulant/Antiplatelet Considerations

  • Do not withhold, reverse anticoagulation, or administer blood products for non-life-threatening epistaxis 1, 4
  • First-line local control measures should always be attempted before considering any anticoagulation reversal 4
  • For aspirin in high-risk cardiovascular patients (recent MI or stents), continue aspirin despite epistaxis—survival benefits outweigh bleeding risks 2
  • Reversal agents (4-factor prothrombin complex concentrate) should only be used for life-threatening bleeding due to significant thrombotic risk 4

NSAID-Related Epistaxis

  • Manage with standard epistaxis protocol without discontinuing NSAIDs unless bleeding cannot be controlled with local measures 2
  • NSAIDs cause significant platelet dysfunction but standard epistaxis alone is not an indication to stop 2

Prevention of Recurrence

  • Apply petroleum jelly or other lubricating agents to the nasal mucosa once bleeding stops 1, 3, 2, 4
  • Use saline nasal sprays regularly to keep nasal passages moist 3, 2, 4
  • Consider using a humidifier, especially in dry environments 3, 4
  • Avoid nose picking, vigorous nose blowing, and nasal decongestants for at least 7-10 days 2

When to Escalate Care

Indications for Prompt Management

  • Distinguish patients requiring prompt management based on bleeding duration, hemodynamic instability (tachycardia, hypotension), or history of hospitalization for epistaxis 1, 2
  • Seek immediate medical attention if bleeding does not stop after 15 minutes of continuous pressure 3, 4
  • Signs requiring urgent evaluation: dizziness from blood loss, severe bleeding (>30 minutes duration over 24 hours), hemodynamic instability 3

Surgical Options for Refractory Cases

  • Endoscopic sphenopalatine artery ligation has 97% success rate versus 62% for conventional packing 2, 6
  • Endovascular embolization has 80% success rate with comparable efficacy to surgical methods 2, 6
  • Both surgical ligation and embolization have lower recurrence rates (<10%) compared to nasal packing (50%) 2, 6

Documentation Requirements

  • Document factors increasing bleeding frequency or severity: personal or family history of bleeding disorders, anticoagulant or antiplatelet use, intranasal drug use 1, 2
  • Follow-up within 30 days for patients who underwent invasive treatments to assess complications and recurrent bleeding 2

Note on Ice Packs: Current evidence does not support ice packs as a first aid intervention for acute epistaxis—it does not significantly change nasal blood flow or volume 2

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Epistaxis Management

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Guideline

Management of Epistaxis in Patients on Ozempic (Semaglutide)

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Management of Nosebleeds in Patients Taking Anticoagulants

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Epistaxis Treatment Options: Literature Review.

Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India, 2023

Research

Epistaxis: Outpatient Management.

American family physician, 2018

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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