What is the recommended dose of elemental zinc syrup for a 1-year-old infant weighing 8kg?

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Zinc Syrup Dosing for a 1-Year-Old Weighing 8kg

For a 1-year-old infant weighing 8kg, administer 0.8 mg (800 μg) of elemental zinc daily for routine supplementation, which translates to approximately 0.8 mL of zinc syrup if using a standard 1 mg/mL concentration. 1

Standard Dosing Calculation

  • For infants 3-12 months of age, the recommended dose is 100 μg/kg/day of elemental zinc 1, 2
  • For this 8kg infant: 100 μg/kg/day × 8 kg = 800 μg (0.8 mg) daily 1
  • The American Academy of Pediatrics specifically recommends 100 μg/kg/day for 1-year-old children 1

Important Dosing Transition at 12 Months

  • After 12 months of age, the dosage decreases to 50 μg/kg/day, with a maximum of 5 mg/day for routine supplementation 1, 3
  • This represents a significant reduction in weight-based dosing as children transition beyond infancy 1

Administration Guidelines

  • Administer zinc between meals rather than with food for optimal absorption 1, 3
  • Divide the dose throughout the day for better tolerability 1, 3
  • Avoid giving zinc with foods high in phytates, which significantly reduce absorption 1, 3

Special Circumstances Requiring Higher Doses

For Documented Zinc Deficiency

  • Therapeutic doses of 0.5-1 mg/kg/day (4-8 mg daily for this 8kg infant) should be given for 3-4 months 1, 4

For Acute Diarrhea

  • If treating diarrhea in zinc-deficient populations: 10 mg elemental zinc daily for 10-14 days for infants under 6 months, or 20 mg daily for children 6 months to 5 years 4, 5
  • This is substantially higher than routine supplementation and should not be confused with maintenance dosing 3

Critical Safety Considerations

  • Monitor for vomiting, which is the most common adverse effect of zinc supplementation 6
  • For children on long-term zinc supplementation, monitor serum zinc levels and alkaline phosphatase periodically 1, 3
  • Do not exceed recommended doses—acute toxicity can occur with excessive zinc administration 1, 2

Common Pitfall to Avoid

  • Do not confuse routine supplementation doses (100 μg/kg/day) with therapeutic doses for deficiency (0.5-1 mg/kg/day)—this represents a 5-10 fold difference 1, 3
  • If co-supplementing with iron, be aware that iron may decrease the beneficial effects of zinc 6

References

Guideline

Zinc Supplementation Guidelines for Children

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Daily Zinc Supplementation Guidelines for Children

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Zinc Supplementation for Infants Under 6 Months of Age

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Role of zinc in pediatric diarrhea.

Indian journal of pharmacology, 2011

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Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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