What is the diagnosis for a 28-year-old woman with a persistent breast cyst after fine-needle aspiration?

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Differential Diagnosis for a Painful Breast Mass

  • Single most likely diagnosis
    • Fibroadenoma: This is a common benign breast tumor, especially in young women. The mass is described as soft, mobile, and tender, which is consistent with a fibroadenoma. The fact that the mass remains palpable after aspiration of a cystic component suggests a solid component, which is typical of fibroadenomas.
  • Other Likely diagnoses
    • Breast cyst with a solid component: Although the ultrasound showed a thin-walled, fluid-filled cyst, the presence of a solid component cannot be ruled out. The fact that the mass is still palpable after aspiration suggests that there may be a solid component to the cyst.
    • Phyllodes tumor: This is a rare tumor of the breast that can be benign, borderline, or malignant. It can present as a rapidly growing mass, but it can also be slow-growing and mobile, similar to the mass described in this patient.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed)
    • Breast cancer: Although breast cancer is less common in young women, it is still a possibility and should not be missed. The fact that the mass is palpable and tender does not rule out cancer, and further evaluation with imaging and biopsy may be necessary.
    • Inflammatory breast cancer: This is a rare and aggressive form of breast cancer that can present with a palpable mass, skin changes, and nipple discharge. Although the patient does not have skin changes or nipple discharge, inflammatory breast cancer should still be considered.
  • Rare diagnoses
    • Hamartoma: This is a rare benign breast tumor that can present as a palpable mass. It is usually asymptomatic, but it can cause pain and tenderness.
    • Lipoma: This is a rare benign breast tumor that can present as a palpable mass. It is usually asymptomatic, but it can cause pain and tenderness.
    • Pseudoangiomatous stromal hyperplasia (PASH): This is a rare benign breast lesion that can present as a palpable mass. It is usually asymptomatic, but it can cause pain and tenderness.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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