What are the causes of periorbital (around the eye) edema?

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Last updated: April 10, 2025View editorial policy

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From the Research

Periorbital edema is most commonly caused by infections, allergic reactions, trauma, and systemic conditions, and its treatment depends on the underlying cause, as evident from the study published in 2012 1. The causes of periorbital edema can be categorized into several groups, including:

  • Infectious causes, such as conjunctivitis, sinusitis, or cellulitis, which can lead to inflammation and swelling, as discussed in the study published in 2021 2
  • Allergic reactions to foods, medications, or environmental allergens, which trigger histamine release and fluid accumulation
  • Trauma or injury to the eye area, including surgical procedures, which can result in temporary swelling
  • Systemic conditions, such as kidney disease, heart failure, or thyroid disorders, which can cause fluid retention throughout the body, including around the eyes
  • Other causes, such as excessive salt intake, alcohol consumption, crying, or rubbing the eyes, which can contribute to temporary swelling It is essential to note that the treatment of periorbital edema depends on the underlying cause, and may include antihistamines for allergies, antibiotics for infections, diuretics for fluid retention, or simply elevating the head while sleeping and applying cold compresses to reduce swelling, as mentioned in the study published in 2007 3. In some cases, periorbital edema can be a symptom of a more serious condition, such as orbital cellulitis, which requires immediate diagnosis and treatment to avoid serious complications, as discussed in the study published in 2016 4. Therefore, it is crucial to distinguish between allergic and infectious causes of periorbital swelling, as delayed diagnosis can lead to serious complications, as reported in the study published in 2004 5. The most effective approach to managing periorbital edema is to identify the underlying cause and provide targeted treatment, as supported by the study published in 2012 1.

References

Research

Periorbital edema: a puzzle no more?

Current opinion in ophthalmology, 2012

Research

Corticosteroids for periorbital and orbital cellulitis.

The Cochrane database of systematic reviews, 2021

Research

Fever and periorbital edema: a review.

Survey of ophthalmology, 2007

Research

Diagnosis, management and treatment of orbital and periorbital cellulitis in children.

Emergency nurse : the journal of the RCN Accident and Emergency Nursing Association, 2016

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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