What is the typical Mental Status Examination (MSE) format for a patient presenting with moderate depression?

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Mental Status Examination Format for Psychiatric Consultations

The Mental Status Examination should follow a structured nine-domain format: Appearance, Behavior, Speech, Mood and Affect, Thought Process, Thought Content, Perceptual Disturbances, Cognition/Sensorium, and Insight/Judgment. 1, 2

Core MSE Domains

1. Appearance

  • Document grooming, hygiene, dress appropriateness, and physical presentation 1, 3
  • Note any signs of self-neglect or unusual attire that may indicate psychiatric disturbance 1

2. Behavior and Motor Activity

  • Observe general demeanor, eye contact, cooperation level, and psychomotor activity 1, 4
  • Document agitation, retardation, abnormal movements, or catatonic features 1, 3

3. Speech

  • Assess rate, volume, tone, fluency, and spontaneity 1, 4
  • Note pressured speech, poverty of speech, or other abnormalities 3

4. Mood and Affect

  • Mood is the patient's subjective emotional state (ask directly: "How is your mood?") 1, 3
  • Affect is your objective observation of emotional expression, including range, appropriateness, and congruence with mood 1, 3

5. Thought Process

  • Evaluate the organization and flow of thoughts 1, 3
  • Document tangentiality, circumstantiality, flight of ideas, loose associations, or thought blocking 1, 2

6. Thought Content

  • Always assess for suicidal ideation, homicidal ideation, and self-harm thoughts—this must never be omitted regardless of presentation 5, 6
  • Document delusions, obsessions, preoccupations, or paranoia 1, 3
  • For moderate depression specifically, suicidal thoughts are not rare and require frequency and specificity assessment 5

7. Perceptual Disturbances

  • Screen for hallucinations (auditory, visual, tactile, olfactory, gustatory) 1, 3
  • Assess for illusions or depersonalization/derealization 3, 2

8. Cognition and Sensorium

  • Orientation: person, place, time, situation 1, 3
  • Attention and concentration: serial 7s or spelling "WORLD" backwards 3
  • Memory: immediate recall, short-term (5-minute recall), and long-term 1, 3
  • Executive function: abstraction, judgment in hypothetical scenarios 3
  • Consider formal screening tools like Mini-Mental State Examination or Mini-Cog when cognitive impairment is suspected 5, 3

9. Insight and Judgment

  • Assess patient's awareness of their illness and need for treatment 1, 3
  • Evaluate decision-making capacity and understanding of consequences 1, 2

Critical Considerations for Moderate Depression

Immediate Safety Assessment

  • If any risk of self-harm or harm to others is identified, immediately refer for emergency psychiatric evaluation, facilitate a safe environment, implement one-to-one observation, and initiate risk reduction interventions 5
  • The presence of psychosis, severe agitation, or confusion (delirium) also warrants emergency evaluation 5

Rule Out Medical Causes First

  • Before attributing symptoms to depression, exclude uncontrolled pain, fatigue, delirium from infection or electrolyte imbalance, thyroid disorders, and medication side effects 7, 8, 6
  • Perform careful evaluation for altered mental status or unexplained vital sign abnormalities 5

Functional Impairment Documentation

  • Document how symptoms interfere with work, relationships, self-care, and daily activities 5, 7
  • For moderate depression (PHQ-9 score 8-14), expect mild to moderate functional impairment 5

Practical Implementation

Interview Strategy

  • Interview patient and collateral sources (family, caregivers) both together and separately 5
  • Patients frequently minimize symptom severity, making collateral information essential 5
  • For adolescents, discuss confidentiality limits before interviewing alone 5

Documentation Structure

  • Use a standardized format to ensure comprehensive coverage of all domains 9
  • Structured MSE forms significantly improve report quality and comprehensiveness 9
  • The ABC-STAMPS mnemonic (Appearance, Behavior, Cooperation; Speech, Thought process and content, Affect, Mood, Perceptions, Suicidality) provides a systematic framework 4

Common Pitfalls to Avoid

  • Never omit the suicidal ideation assessment—doing so artificially lowers risk detection and misses critical safety information 5, 6
  • Do not rely solely on symptom counts; assess functional impairment and duration 5
  • Avoid using PHQ-9 in patients with cognitive impairment, as it loses accuracy in this population 6
  • Do not confuse mood (subjective) with affect (objective observation) 1, 3

References

Research

Mental status exam in primary care: a review.

American family physician, 2009

Research

Mapping the Mental Status Examination: Insights from a Scoping Review of Popular Psychiatry Textbooks.

Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry, 2025

Research

The Mental Status Examination.

American family physician, 2016

Research

The Mental Status Exam: An Online Teaching Exercise Using Video-Based Depictions by Simulated Patients.

MedEdPORTAL : the journal of teaching and learning resources, 2020

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Diagnostic Criteria for Major Depressive Disorder

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Clasificación de Gravedad del Episodio Depresivo

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Assessment and Management of Depression

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Introduction of a standardized report form improves the quality of mental status examination reports by psychiatry residents.

Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry, 1990

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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