How does Voquenza (Lefamulin) work?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: April 10, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Research

Voquenza is not a recognized medical term, however, based on the provided evidence, it appears that the question may be referring to oseltamivir, an antiviral medication used to treat influenza. The medication works by inhibiting the neuraminidase glycoprotein, which is essential for the replication of influenza A and B viruses 1. Oseltamivir is a prodrug that is converted to its active form, oseltamivir carboxylate, which then selectively inhibits the neuraminidase enzyme, preventing the release of new viral particles from infected cells 2. This mechanism of action reduces the duration and severity of influenza symptoms, and can also prevent the development of secondary complications such as pneumonia and bronchitis 3. In geriatric patients, oseltamivir has been shown to be effective in reducing mortality and complications associated with influenza, and is considered a first-line treatment option 4. However, it is essential to note that the effectiveness of oseltamivir can be influenced by factors such as the timing of treatment initiation, the severity of the infection, and the presence of underlying medical conditions 5. Some key points to consider when using oseltamivir include:

  • The medication should be initiated as soon as possible after the onset of symptoms, ideally within 24-48 hours 3
  • The recommended dosage is 75 mg twice daily for 5 days, although this may vary depending on the patient's age, weight, and renal function 1
  • Oseltamivir can be used for both treatment and prevention of influenza, and is effective against both influenza A and B viruses 2
  • Common side effects include nausea, vomiting, and diarrhea, although these are generally mild and transient 1

References

Research

Influenza and Influenza Vaccine: A Review.

Journal of midwifery & women's health, 2021

Research

Treatment and prevention of influenza in geriatric patients.

Expert review of clinical pharmacology, 2023

Research

How to manage antivirals in critically ill patients with Influenza?

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.