Differential Diagnosis for Euthyroid Causes of Periorbital Edema
Single Most Likely Diagnosis
- Allergic reactions: This is often the most common cause of periorbital edema in euthyroid individuals. Allergies to cosmetics, pollen, or other environmental factors can lead to swelling around the eyes.
Other Likely Diagnoses
- Sinusitis: Inflammation of the sinuses can cause periorbital edema due to the close proximity of the sinuses to the eyes.
- Dermatitis: Contact dermatitis or atopic dermatitis can cause swelling and redness around the eyes.
- Insect bites or stings: Reactions to insect bites or stings can lead to localized edema, including periorbital edema.
Do Not Miss Diagnoses
- Angioedema: A potentially life-threatening condition that can cause rapid swelling of the face, lips, tongue, and throat. It requires immediate medical attention.
- Cellulitis: A bacterial infection of the skin and subcutaneous tissue that can cause swelling, redness, and warmth around the eyes.
- Orbital cellulitis: An infection of the tissues surrounding the eye, which can be serious and vision-threatening if not promptly treated.
Rare Diagnoses
- Wegener's granulomatosis: A rare autoimmune disorder that can cause inflammation and damage to various parts of the body, including the eyes.
- Sarcoidosis: A condition characterized by the growth of granulomas in various organs, including the skin and eyes, which can lead to periorbital edema.
- Amyloidosis: A group of diseases caused by the accumulation of abnormal proteins (amyloid) in various tissues, including the skin and eyes, which can cause periorbital edema.