What are the differential diagnoses for a red eye?

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Last updated: April 10, 2025View editorial policy

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Differential Diagnosis for Red Eye

The differential diagnosis for red eye is extensive and can be categorized into several groups. Here's a breakdown of the possible causes:

  • Single Most Likely Diagnosis
    • Conjunctivitis: This is the most common cause of red eye, often due to viral or bacterial infections. It's characterized by redness, discharge, and irritation of the conjunctiva.
  • Other Likely Diagnoses
    • Dry Eye Syndrome: Insufficient tear production or poor tear quality can cause redness, irritation, and discomfort.
    • Blepharitis: Inflammation of the eyelids can lead to redness, itching, and swelling.
    • Subconjunctival Hemorrhage: A broken blood vessel under the conjunctiva can cause sudden onset of redness.
    • Allergic Conjunctivitis: An allergic reaction can cause redness, itching, and watery discharge.
  • Do Not Miss Diagnoses
    • Acute Angle-Closure Glaucoma: A medical emergency that can cause severe eye pain, redness, and vision loss.
    • Corneal Ulcer: A bacterial or fungal infection of the cornea that can lead to severe vision loss if left untreated.
    • Endophthalmitis: A rare but serious infection of the inner eye that can cause severe vision loss and pain.
    • Scleritis: Inflammation of the sclera that can cause severe eye pain, redness, and vision loss.
  • Rare Diagnoses
    • Keratoconus: A progressive thinning of the cornea that can cause vision distortion and redness.
    • Uveitis: Inflammation of the uvea that can cause eye pain, redness, and vision loss.
    • Sjögren's Syndrome: An autoimmune disorder that can cause dry eye and other systemic symptoms.
    • Erythema Multiforme: A skin condition that can cause red, target-shaped lesions on the eyes and skin.

Each of these diagnoses has distinct characteristics and requires a thorough medical evaluation to determine the underlying cause of the red eye.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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