From the Guidelines
In Canada, irbesartan (not ibisarten) is available primarily in oral tablet form, with strengths of 75 mg, 150 mg, and 300 mg, as indicated in the dosage guidelines 1. The typical starting dose is 150 mg once daily, which may be increased to 300 mg once daily if needed for blood pressure control, as recommended in the clinical practice guidelines 1. For patients with volume depletion (such as those on diuretics), a lower starting dose of 75 mg may be recommended, as suggested in the evidence 1. Irbesartan can be taken with or without food at the same time each day to maintain consistent blood levels, and it works by blocking the action of angiotensin II, a natural substance that narrows blood vessels, which helps blood vessels relax and lowers blood pressure, as described in the guidelines 1. Some key points to consider when prescribing irbesartan include:
- The full blood pressure-lowering effect may take 2-4 weeks to develop after starting treatment, as noted in the evidence 1
- Irbesartan is an angiotensin II receptor blocker (ARB) used to treat high blood pressure and protect kidney function in people with type 2 diabetes who have kidney problems, as indicated in the guidelines 1
- Patients should be aware of the potential risks and benefits of irbesartan, including the risk of hyperkalemia and the importance of regular monitoring of kidney function and blood pressure, as recommended in the clinical practice guidelines 1
From the FDA Drug Label
Irbesartan is available for oral administration in unscored tablets containing 75 mg, 150 mg, or 300 mg of Irbesartan USP. The dosage forms of pills for irbesartan are:
- Tablets: 75 mg, 150 mg, or 300 mg 2 Note that the question asks about ibisarten, but the provided drug labels are for irbesartan. Assuming the question intended to ask about irbesartan, the answer is provided above. If the question indeed asks about ibisarten, then The FDA drug label does not answer the question.
From the Research
Dosage Forms of Irbesartan in Canada
- The available evidence does not specifically mention the dosage forms of irbesartan in Canada 3, 4, 5, 6, 7.
- However, the studies provide information on the dosages of irbesartan used in various clinical trials, such as 75 mg to 300 mg per day 5, 100 mg per day 6, 7, and combination therapies with other antihypertensive agents like hydrochlorothiazide, amlodipine, and indapamide 4, 6, 7.
- The dosage forms of irbesartan are not explicitly stated in the provided studies, but it can be inferred that irbesartan is available in tablet form, given the dosages mentioned in the studies 3, 4, 5, 6, 7.
Available Dosages
- The studies mention the following dosages of irbesartan: