Can Vitamin C (Vit C) cause Gastroesophageal Reflux Disease (GERD)?

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Last updated: April 10, 2025View editorial policy

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From the Research

Vitamin C can potentially cause or worsen GERD symptoms in some individuals, particularly when taken in high doses or in acidic forms. The acidity of vitamin C supplements can irritate the esophagus and trigger acid reflux symptoms 1. If you experience GERD and want to take vitamin C, consider using buffered or non-acidic forms like calcium ascorbate or sodium ascorbate instead of ascorbic acid. Some key points to consider when taking vitamin C with GERD include:

  • Start with lower doses (250-500mg) and gradually increase if tolerated
  • Take vitamin C supplements with food rather than on an empty stomach to help minimize irritation
  • Be aware that the mechanism behind this reaction is straightforward: vitamin C is naturally acidic, and introducing additional acid into an already sensitive digestive system can disrupt the balance and trigger reflux
  • If you notice worsening GERD symptoms after taking vitamin C supplements, reduce your dosage or discontinue use and consult with a healthcare provider about alternative options for meeting your vitamin C needs through diet or specialized supplements 2, 3. It's also important to note that lifestyle changes, such as weight loss and smoking cessation, can be beneficial in managing GERD symptoms 2. Additionally, medication and surgery are also treatment options for GERD, and the clinical management of GERD influences the lives of many individuals and is responsible for substantial consumption of health care and societal resources 1.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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