Are zinc supplements beneficial for patients with End-Stage Renal Disease (ESRD)?

For ESRD patients, zinc supplements may be beneficial in addressing potential zinc deficiencies, which can be common due to poor dietary intake, inflammation, and dialysis-related losses. However, it's essential to exercise caution when recommending zinc supplements, as excessive zinc intake can be toxic. A reasonable approach would be to recommend a moderate dose of zinc, such as 15-20 mg per day, under the close supervision of a healthcare provider. The patient's kidney function, dialysis schedule, and other medications should be carefully monitored to avoid any potential interactions or adverse effects. In addition to zinc supplements, ESRD patients may also benefit from a balanced diet that includes zinc-rich foods, such as lean meats, seafood, and fortified cereals. Second-line interventions may include adjusting the patient's dialysis schedule or prescription medications to minimize zinc losses and optimize zinc levels. Ultimately, the decision to recommend zinc supplements should be made on a case-by-case basis, taking into account the individual patient's unique medical history, nutritional status, and laboratory results.