What is the recommended intraosseous (IO) line placement site for a 3-year-old patient requiring immediate vascular access?

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Last updated: January 5, 2026View editorial policy

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Recommended IO Site for a 3-Year-Old

For a 3-year-old child requiring intraosseous access, use the proximal tibia as the primary site, with insertion 1-3 cm below the tibial tuberosity on the flat anteromedial surface. 1, 2

Primary Site: Proximal Tibia

  • The proximal tibia is the preferred and most commonly used site for pediatric IO access in children under 5 years of age. 1, 2
  • Insert the needle 1-3 cm below the tibial tuberosity on the flat anteromedial surface of the tibia. 2
  • At 3 years of age, the medullary diameter is approximately 12 mm, providing adequate space for proper needle positioning. 3
  • Use a 25-mm IO needle for this age group, which has demonstrated success rates of 87.5-91.1% in children 13-24 months and older. 4

Alternative Site: Distal Femur

  • The distal femur is an acceptable alternative site that may offer marginally higher success rates (89.0% vs 84.7%) compared to the proximal tibia. 5
  • Consider the distal femur particularly if the proximal tibia site is inaccessible, traumatized, or if initial tibial placement fails. 5
  • The distal femur site is located 1 cm superior to the distal femur physis. 4

Critical Technical Considerations

  • Confirm correct needle placement immediately by aspirating bone marrow and administering a test fluid bolus. 3
  • Avoid the 25-mm needle in infants under 6 months (failure rate of 100% in one study), but this is not a concern for a 3-year-old. 6
  • Insert a luer-lock catheter with a three-way stopcock to minimize needle manipulation after placement. 3
  • Use manual pressure or an infusion pump for viscous drugs or rapid fluid boluses, followed by saline flush. 1

Important Safety Warnings

  • Remove the IO device as soon as alternative IV access is established, ideally within 24 hours. 7, 3
  • Monitor continuously for compartment syndrome, extravasation, and limb perfusion abnormalities. 1, 3
  • Serious complications including fractures, compartment syndrome, and amputation have been reported, particularly with prolonged use or malpositioned needles. 1, 6, 3
  • Avoid infusing inotropic medications through IO access after the initial resuscitation phase. 3

Medications and Fluids

  • All intravenous medications can be administered intraosseously, including epinephrine, adenosine, fluids, blood products, and catecholamines. 1
  • Drug onset and levels are comparable to IV administration. 1
  • Follow each medication with a saline flush to promote entry into central circulation. 1

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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