From the Guidelines
The recommended dosing frequency of Tessalon (Benzonatate) is 100-200 mg taken three to four times a day.
Key Points
- The dosing frequency is based on the provided evidence from the Chest guideline and expert panel report 1.
- The indicative dose for Benzonatate is listed as 100-200 mg qid, which translates to three to four times a day.
- It is essential to note that the dose may vary depending on the country and availability of the medication.
- As with any medication, it is crucial to follow the prescribed dosage and consult with a healthcare professional for specific guidance.
- The evidence suggests that Benzonatate is a peripherally acting antitussive, and its use may be considered for patients with lung cancer experiencing cough, especially when other treatments have failed 1.
From the FDA Drug Label
Adults and Children over 10 years of age: Usual dose is one 100 mg or 200 mg capsule three times a day as needed for cough. If necessary to control cough, up to 600 mg daily in three divided doses may be given. The recommended dosing frequency of Tessalon (Benzonatate) is three times a day as needed for cough, with a maximum of three divided doses daily 2.
- The dose can be either 100 mg or 200 mg per administration.
- The maximum daily dose is 600 mg.
From the Research
Recommended Dosing Frequency of Tessalon (Benzonatate)
- The recommended dosing frequency of Tessalon (Benzonatate) is not explicitly stated in the provided studies 3, 4, 5, 6, 7.
- However, the studies report on the toxicity and overdose of Benzonatate, suggesting that the medication should be used with caution and under medical supervision.
- The studies do not provide information on the recommended dosing frequency, but rather highlight the potential risks associated with overdosing or misuse of the medication.
Overdose Risks and Considerations
- The studies report on several cases of Benzonatate overdose, resulting in cardiac arrest, respiratory failure, and other life-threatening complications 3, 5, 6.
- The risk of overdose and toxicity is a concern, particularly in pediatric patients and individuals who may be prone to misuse or accidental ingestion.
- The studies emphasize the importance of rational prescribing and patient education to minimize the risk of overdose and ensure safe use of the medication.
Clinical Use and Safety
- Benzonatate is a widely prescribed antitussive medication, and its safety and efficacy have been demonstrated in various clinical studies 4, 7.
- However, the medication should be used with caution, and patients should be closely monitored for signs of toxicity or overdose.
- The studies suggest that Benzonatate and its metabolites are not genotoxic or carcinogenic, but further research is needed to fully assess the safety profile of the medication 4, 7.