From the FDA Drug Label
Active ingredient (per softgel) Simethicone 180 mg Use for the relief of pressure and bloating commonly referred to as gas The recommended dosage of simethicone for bloating is not explicitly stated in the provided drug labels. However, based on the available information, simethicone is used for the relief of pressure and bloating. The dosage of simethicone is 180 mg per softgel 1. It is used for the relief of gas 1.
- The drug name is simethicone (PO) 1, 1
- The active ingredient is simethicone 180 mg 1
- The use is for the relief of pressure and bloating 1
From the Research
The recommended dosage of simethicone for bloating is typically 125-250 mg taken after meals and at bedtime, up to four times daily, as it has been shown to decrease bloating and improve bowel preparation effectiveness 2.
Key Considerations
- For adults and children 12 years and older, one to two tablets (or softgels) containing 125 mg each can be taken.
- Children aged 2-12 should take only 40-95 mg per dose, and the medication is not recommended for children under 2 without medical advice.
- Simethicone works by breaking up gas bubbles in the digestive tract, making them easier to eliminate, and begins working within 30 minutes.
Important Safety Information
- While simethicone is generally safe with minimal side effects, the maximum daily dosage of 500 mg should not be exceeded.
- If bloating persists beyond two weeks or is accompanied by severe pain, fever, or changes in bowel habits, a healthcare provider should be consulted as these symptoms may indicate a more serious condition requiring different treatment.
Evidence Summary
- A systematic review and meta-analysis found that simethicone improves colon cleanliness and decreases abdominal bloating, but has no effect on nausea, vomiting, and abdominal pain 2.
- Other studies have investigated the efficacy of peppermint oil in irritable bowel syndrome, but simethicone remains a recommended treatment for bloating due to its proven effectiveness and safety profile.