ICD-10 Codes for Standard STD Screening Panel
The standard STD check includes testing for chlamydia, gonorrhea, syphilis, and HIV, with specific ICD-10 codes used for screening asymptomatic individuals versus diagnostic testing for those with symptoms or known exposures.
Primary Screening Codes for Asymptomatic Patients
Encounter Codes (Z-codes)
- Z11.3 - Encounter for screening for infections with a predominantly sexual mode of transmission 1, 2
- Z11.4 - Encounter for screening for human immunodeficiency virus [HIV] 1, 2
- Z11.59 - Encounter for screening for other viral diseases (for hepatitis B and C screening) 1, 2
Risk Factor Documentation Codes
- Z72.51 - High-risk heterosexual behavior 1, 2
- Z72.52 - High-risk homosexual behavior 1, 2
- Z72.53 - High-risk bisexual behavior 1, 2
- Z77.21 - Contact with and (suspected) exposure to potentially hazardous body fluids 1, 2
Standard Testing Components
Core STD Panel Tests
- Chlamydia testing should use Z11.3 for screening in sexually active women ≤25 years or those with risk factors (new/multiple partners) 1, 2
- Gonorrhea testing should use Z11.3 for screening in sexually active women <25 years and high-risk individuals 1, 2
- HIV testing should use Z11.4 for all sexually active persons not in mutually monogamous relationships with uninfected partners 1, 2
- Syphilis testing should use Z11.3 for individuals with high-risk sexual behavior or in high-prevalence communities 1, 2
Additional Tests Often Included
- Hepatitis B screening uses Z11.59, particularly for pregnant women and high-risk individuals 1, 2
- Hepatitis C screening uses Z11.59 based on risk factors 1, 2
- Trichomoniasis testing uses Z11.3 for women with symptoms or high risk 1, 2
Site-Specific Testing Codes for High-Risk Populations
Men Who Have Sex with Men (MSM)
- Use Z11.3 for urogenital, rectal, and pharyngeal chlamydia and gonorrhea testing based on reported sexual practices 3, 1, 2
- Testing should occur at all three anatomic sites since infections are frequently asymptomatic and site-specific 3, 4
Pregnant Women
- Use Z11.3 for chlamydia and gonorrhea if <25 years or at increased risk 3, 2
- Use Z11.4 for universal HIV screening at first prenatal visit 3, 2
- Use Z11.3 for syphilis screening at first prenatal visit, with repeat testing in third trimester and at delivery for high-risk women 3, 2
- Use Z11.59 for hepatitis B surface antigen testing at first prenatal visit 3, 2
Diagnostic Codes When Symptoms Present
Critical distinction: Once symptoms develop or there is known exposure, testing becomes diagnostic rather than screening, requiring different ICD-10 codes 5:
- A54.xx - Gonococcal infection codes (when symptomatic or contact)
- A55 - Chlamydial lymphogranuloma (venereum)
- A56.xx - Other sexually transmitted chlamydial diseases
- A51.xx-A53.xx - Syphilis codes (various stages)
- B20 - HIV disease
- A59.xx - Trichomoniasis codes
Frequency-Based Coding Considerations
Annual Screening
- Use Z11.3 or Z11.4 for routine annual screening in at-risk populations 1, 2
- Document risk factors with Z72.51-Z72.53 codes to justify medical necessity 1, 2
High-Frequency Screening (Every 3-6 Months)
- Use Z11.3 or Z11.4 with additional risk factor codes for individuals with ongoing high-risk behaviors including multiple partners, inconsistent condom use, or drug use during sex 3, 1, 2
- HIV-infected individuals with high-risk behaviors warrant every 3-6 month testing regardless of previous negative results 3, 2
Post-Treatment Rescreening
- Use Z09 (encounter for follow-up examination after completed treatment) combined with Z11.3 for mandatory 3-month retesting after chlamydia or gonorrhea treatment 1, 2
- This rescreening is essential due to 25-40% reinfection rates 2
Common Coding Pitfalls to Avoid
- Never use screening codes (Z11.x) when symptoms are present - this constitutes fraud and will result in claim denials 5
- Document sexual history and risk factors to support medical necessity for screening frequency beyond annual intervals 3, 1
- Use site-specific codes when billing for extragenital testing (rectal/pharyngeal) in MSM populations 3, 4
- Ensure proper sequencing - list the screening code (Z11.x) as primary diagnosis, with risk factor codes (Z72.5x) as secondary 1, 2
Special Population Considerations
Adolescents and Young Adults
- Z11.3 is appropriate for all sexually active women under 25 years for chlamydia and gonorrhea screening 1, 2
- Higher infection rates in this age group due to more frequent partner changes and cervical immaturity justify routine screening 2
Persons Who Use Drugs
- Use Z11.3 for routine screening for all common STIs including chlamydia, gonorrhea, syphilis, and trichomoniasis 2
- Use Z11.59 for hepatitis C screening for all who inject drugs, even if only once 2
Correctional Facility Entrants
- Use Z11.3 for screening persons entering correctional facilities for syphilis, gonorrhea, and chlamydia 2