Plan of Care for Acute Bronchitis
Antibiotics should NOT be prescribed for uncomplicated acute bronchitis in otherwise healthy adults, as they provide minimal benefit (reducing cough by only half a day) while exposing patients to adverse effects and contributing to antibiotic resistance. 1, 2
Initial Evaluation: Rule Out Serious Illness
The primary goal is to exclude pneumonia and other serious conditions before confirming acute bronchitis. 1
Key clinical indicators that suggest pneumonia rather than bronchitis:
- Heart rate >100 beats/min 2
- Respiratory rate >24 breaths/min 2
- Oral temperature >38°C 2
- Abnormal lung examination findings (rales, egophony, tactile fremitus, or asymmetrical lung sounds) 1, 2
When chest radiography is indicated:
- If any vital sign abnormalities or focal lung findings are present 1
- If cough persists ≥3 weeks without other known causes 1
- In healthy, nonelderly adults without these findings, chest radiography is usually not indicated 1
Other diagnoses to exclude:
- Common cold (predominantly upper respiratory symptoms) 1
- Asthma exacerbation (wheezing, history of asthma) 1, 2
- COPD exacerbation (in patients with known COPD) 1, 2
Antibiotic Treatment: When NOT to Prescribe
The evidence is unequivocal: routine antibiotic treatment is not recommended regardless of cough duration. 1, 2
Critical points about antibiotics:
- Respiratory viruses cause 89-95% of acute bronchitis cases 2
- Purulent sputum occurs in 89-95% of viral cases and does NOT indicate bacterial infection 2
- Sputum color change is NOT an indication for antibiotics 2
- Antibiotics reduce cough duration by only approximately 0.5 days 2, 3
- Antibiotics cause adverse effects including allergic reactions, nausea, vomiting, and Clostridium difficile infection 3
The ONE Exception: Pertussis
If pertussis is suspected or confirmed, prescribe a macrolide antibiotic immediately. 1, 2
Pertussis should be suspected when:
- Cough persists >2 weeks with paroxysmal coughing, whooping cough, or post-tussive vomiting 2
- Recent pertussis exposure is documented 1
Treatment for pertussis:
- Prescribe erythromycin or azithromycin 2
- Isolate patient for 5 days from start of treatment 2
- Early treatment (within first few weeks) diminishes coughing paroxysms and prevents disease spread 2
Symptomatic Treatment Recommendations
Bronchodilators:
- β2-agonist bronchodilators should NOT be routinely used for cough in acute bronchitis 2
- Consider β2-agonists only in select patients with wheezing accompanying the cough 2
Cough suppressants:
- Codeine or dextromethorphan may provide modest effects on cough severity and duration 2
- These agents are most useful when dry cough is bothersome and disturbs sleep 2
What NOT to prescribe:
- Oral corticosteroids (including prednisone) are NOT recommended for uncomplicated acute bronchitis 4
- NSAIDs at anti-inflammatory doses are NOT recommended 2
- Expectorants, mucolytics, antihistamines, or inhaled corticosteroids lack evidence of benefit 2
Low-risk supportive measures:
- Elimination of environmental cough triggers (smoke, irritants) 2
- Vaporized air treatments or humidification 2
- Adequate hydration 2
Patient Education: The Key to Satisfaction
Patient satisfaction depends more on physician-patient communication than whether an antibiotic is prescribed. 1, 2
Essential points to communicate:
- Cough typically lasts 10-14 days after the office visit, even without antibiotics 2, 3
- The condition is self-limiting and resolves within 3 weeks 1, 2
- Antibiotics will not significantly shorten the illness and carry risks 2, 3
- Referring to the condition as a "chest cold" rather than "bronchitis" may reduce patient expectations for antibiotics 2, 3
When to Reassess
Instruct patients to return if:
- Fever persists >3 days (suggests bacterial superinfection or pneumonia) 2
- Cough persists >3 weeks (consider asthma, COPD, pertussis, or gastroesophageal reflux) 1, 2
- Symptoms worsen rather than gradually improve 2
Special Populations Requiring Different Management
These guidelines apply ONLY to otherwise healthy adults with uncomplicated acute bronchitis. 1
Patients requiring individualized management:
- Underlying COPD or chronic bronchitis 1, 2
- Congestive heart failure 1
- Immunosuppression (AIDS, chemotherapy) 1, 2
- Elderly patients (≥75 years) with comorbidities 2
Common Pitfalls to Avoid
- Do not assume purulent sputum indicates bacterial infection – it occurs in 89-95% of viral cases 2
- Do not prescribe antibiotics based on cough duration alone – viral bronchitis cough normally lasts 10-14 days 2
- Do not miss undiagnosed asthma – approximately one-third of patients diagnosed with recurrent "acute bronchitis" actually have asthma 1, 2
- Do not prescribe antibiotics over the phone – physical examination is essential to rule out pneumonia 5