Paradoxical vs Unmasking IRIS: Key Distinctions
I cannot provide a definitive answer to this question because the provided evidence does not contain information about "paradoxical IRIS" or "unmasking IRIS" behaviors in the context requested. The evidence discusses Intraoperative Floppy Iris Syndrome (IFIS), iris-related surgical complications, and various glaucoma and refractive surgery topics, but does not address the specific terminology or clinical entities of "paradoxical" versus "unmasking" IRIS behaviors.
What the Evidence Does Cover
The available guidelines discuss:
Intraoperative Floppy Iris Syndrome (IFIS): A condition during cataract surgery characterized by iris billowing, prolapse, and progressive miosis, strongly associated with α-blocker use (particularly tamsulosin), though the exact pathophysiology remains unclear 1
Iris-related surgical complications: Including irregular pupil formation, iris distortion, pigment dispersion, and iris bombé in various surgical contexts 2
Secondary angle closure mechanisms: Classified as "pulling" (iris membranes, neovascularization) or "pushing" (pupillary block, lens displacement) mechanisms 2
Clinical Recommendation
If you are asking about immune reconstitution inflammatory syndrome (IRIS) in the context of infectious uveitis or systemic infections affecting the eye, this would require different evidence sources focused on infectious disease and uveitis management. The ophthalmology guidelines provided do not address this immunologic phenomenon.
If you are asking about a different iris-related phenomenon specific to glaucoma or intraocular surgery, please clarify the clinical context (e.g., post-laser iridotomy inflammation, post-surgical inflammatory responses, or specific drug-related iris changes) so that the appropriate evidence can be identified and applied.