What is the most likely cause of bilateral knee pain with tender prominence over the tibial tuberosities in a 12-year-old boy, with no history of trauma, who is active in sports and experiences pain after strenuous activity, and has radiographic findings of moderate prominence of the tibial tuberosities and mild soft tissue edema?

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Differential Diagnosis for Knee Pain in a 12-year-old Boy

  • Single most likely diagnosis
    • D) Repetitive quadriceps contraction: This is the most likely cause of the findings, as the patient's symptoms and examination results are consistent with Osgood-Schlatter disease, a condition characterized by inflammation of the patellar tendon at its insertion on the tibial tuberosity, often due to repetitive quadriceps contraction in active adolescents.
  • Other Likely diagnoses
    • B) Increased growth velocity at the start of puberty: This could contribute to the development of Osgood-Schlatter disease, as rapid growth during puberty can lead to inflammation and pain at the sites of tendon insertion.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • A) Bacterial infection of the bone: Although less likely, bacterial infection (osteomyelitis) could present with similar symptoms, including pain and swelling over the affected area, and would require prompt diagnosis and treatment to prevent serious complications.
    • E) Trauma causing subperiosteal hemorrhage: While the patient denies a history of trauma, it is essential to consider this possibility, as a subperiosteal hemorrhage could lead to significant morbidity if not recognized and treated appropriately.
  • Rare diagnoses
    • C) Loss of intraarticular cartilage: This would be an unusual finding in a 12-year-old boy without a history of trauma or systemic disease, and the patient's symptoms and examination results do not suggest intraarticular pathology.
    • Other rare diagnoses, such as tumors or systemic diseases, are not suggested by the patient's presentation and would require additional symptoms or findings to be considered.

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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