What is the cause of a patient's recent onset of underbag (scrotal) swelling?

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Last updated: April 11, 2025View editorial policy

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Differential Diagnosis for Recent Onset of Underbag Swelling

  • Single most likely diagnosis
    • Cellulitis: This is a common cause of swelling, especially if the patient has a history of trauma, insect bites, or skin infections. The recent onset of underbag swelling could be due to bacterial infection of the skin and subcutaneous tissue.
  • Other Likely diagnoses
    • Lymphedema: This condition is characterized by the abnormal accumulation of protein-rich fluid in the interstitial tissue, leading to swelling. It could be primary (genetic) or secondary (due to surgery, infection, or trauma).
    • Deep Vein Thrombosis (DVT): Although less common in the upper extremities, DVT can cause swelling, pain, and warmth in the affected limb.
    • Insect bite or sting: Certain insect bites or stings can cause localized swelling, especially if the patient has an allergic reaction.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Necrotizing fasciitis: A life-threatening infection that requires prompt medical attention. Although rare, it can cause severe swelling, pain, and skin necrosis.
    • Compartment syndrome: A condition that occurs when pressure within the muscle compartments increases, leading to inadequate blood supply and potentially causing permanent damage.
    • Septic arthritis: An infection within a joint that can cause swelling, pain, and limited mobility. If left untreated, it can lead to serious complications.
  • Rare diagnoses
    • Filariasis: A parasitic infection that can cause lymphedema and swelling, typically in tropical regions.
    • Sarcoidosis: A systemic disease that can cause swelling and inflammation in various parts of the body, including the skin and lymph nodes.
    • Angioedema: A rare condition characterized by the rapid onset of swelling, often affecting the face, lips, and extremities. It can be life-threatening if not treated promptly.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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