Can an older adult patient with a history of osteoporosis restart phosphonate (bisphosphonate) therapy after a drug holiday?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board

Educational purpose only • Exercise caution as content is pending human review

Article Review Status

Submitted

Under Review

Approved

Last updated: January 7, 2026 • View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Related Questions

When can bisphosphonates be safely restarted after a 5-year treatment period?

What is the typical duration of a drug holiday from alendronate (bisphosphonate) therapy?

Can a patient with a history of long-term bisphosphonate therapy, typically five years or more, restart bisphosphonates after a drug holiday?

According to the Canadian Medical Association Journal (CMAJ) Osteoporosis guidelines, how long should a patient be on bisphosphonates before a drug holiday and when should they be re-started on medications?

What is the recommended duration of bisphosphonate (e.g. alendronate or risedronate) therapy before considering a drug holiday?

What are the best treatment options for a 3.5-year history of chronic neuropathic pain due to a damaged nerve in the throat, currently managed with 10mg imipramine (tricyclic antidepressant) daily?

What is the recommended treatment for a patient suspected of having a Salmonella infection with severe symptoms, including bloody diarrhea, fever, and signs of dehydration, considering their demographic and medical history?

What are the implications and management of a treatment regimen of 20meq (milliequivalents) of potassium (K+) extended release taken 3 times a day in an adult patient, possibly with a history of cardiovascular disease, kidney disease, or other conditions necessitating careful electrolyte management?

Can a patient with a history of long-term bisphosphonate therapy, typically five years or more, restart bisphosphonates after a drug holiday?

What does a bone marrow blast percentage of 20% indicate for a patient in remission from Acute Myeloid Leukemia (AML)?

What is the diagnosis and treatment for a patient with sclerosis of the caudal margin of the sacroiliac (SI) joints?

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.