What is the appropriate ICD-10 (International Classification of Diseases, 10th Revision) code for a routine screening mammogram in an asymptomatic female patient?

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ICD-10 Code for Routine Screening Mammogram

The appropriate ICD-10 code for a routine screening mammogram in an asymptomatic female patient is Z12.31 1.

Primary Coding Guideline

  • Z12.31 is the specific ICD-10 code designated for encounter for screening mammogram for malignant neoplasm of breast 1
  • This code should be used for all asymptomatic patients with no breast symptoms, signs, or active breast disease who are undergoing routine preventive screening 1
  • The code Z12.31 signifies that the purpose of the encounter is preventive screening rather than diagnostic evaluation 1

When Z12.31 Is Appropriate

  • Asymptomatic women aged 40 and older undergoing annual screening mammography as recommended by ACR and SBI guidelines 2, 1
  • High-risk women under age 40 who qualify for screening mammography, though additional risk factor codes may be beneficial as secondary codes 1
  • Any asymptomatic patient with no palpable masses, breast pain, nipple discharge, or other breast complaints 1

Additional Secondary Codes to Consider

  • Z85.3 should be added as a secondary code if the patient has a personal history of breast cancer 1
  • Z80.3 may be added for patients with family history of malignant neoplasm of breast 1
  • Z15.01 may be used for patients with known genetic mutations (BRCA1/BRCA2) 1
  • Z84.89 may be used for patients with genetic predisposition to breast cancer 1

Critical Coding Pitfalls to Avoid

  • Do not use diagnostic codes (N60-N65 breast disorders) for screening examinations, even if the patient has a history of benign breast disease 1
  • Do not use Z12.39 (general screening for other neoplasm of breast), as Z12.31 is more specific and appropriate 1
  • Do not use Z01.89 (general examination code), as it is too nonspecific for breast cancer screening 1
  • Do not continue using Z12.31 if the screening mammogram reveals an abnormality requiring additional imaging—subsequent diagnostic visits should use appropriate diagnostic codes 1

When to Switch from Screening to Diagnostic Codes

  • If a screening mammogram reveals an abnormality requiring recall or additional imaging, the subsequent encounter should be coded with the appropriate diagnostic code rather than Z12.31 1
  • For short-interval follow-up of probably benign findings (BI-RADS 3), use the appropriate diagnostic code rather than the screening code 1
  • Once a patient develops symptoms or has abnormal findings, they are no longer undergoing screening and diagnostic codes become appropriate 1

References

Guideline

ICD-10 Coding for Screening Mammography

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

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Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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