From the Guidelines
Atherosclerosis in the aorta cannot be reliably diagnosed using X-rays alone, and alternative imaging modalities such as ultrasound, CT angiography, or MRI should be used instead. The presence of atherosclerosis in the aorta is often associated with vascular calcification, which can be seen on imaging studies, but X-rays have limited ability to visualize soft tissue structures like blood vessels and cannot detect the early changes of atherosclerosis 1.
Key Points to Consider
- Vascular calcification occurs in the media and represents a central component of atherogenesis, typically signaling long-standing inflammation 1.
- The amount of calcification directly associates with the extent of atherosclerosis, and the presence of aortic calcium predicts the presence of coronary heart disease 1.
- Severe atherosclerosis of the aorta can cause an eggshell appearance on chest x-ray or CT, also termed “porcelain aorta” 1.
- Alternative imaging modalities such as ultrasound, CT angiography, or MRI can provide detailed information about plaque composition, extent of stenosis, and potential complications like aneurysms.
Recommended Imaging Modalities
- Ultrasound: can visualize the arterial walls and detect plaque buildup, vessel narrowing, and calcifications.
- CT angiography: provides detailed information about plaque composition, extent of stenosis, and potential complications like aneurysms.
- MRI: offers comprehensive evaluation of atherosclerosis throughout the aorta, including plaque composition and extent of stenosis.
Clinical Implications
- If atherosclerosis is suspected based on symptoms or risk factors, consulting with a vascular specialist or cardiologist is recommended to determine the most appropriate imaging study.
- Direct manipulation of the aorta in patients with severe atherosclerosis may result in an unrepairable aortic injury and/or distal embolization, and alternative techniques such as internal aortic balloon occlusion or a “no-touch” technique may be necessary 1.
From the Research
Atherosclerosis Detection on X-rays
- Atherosclerosis is a condition where the arteries become narrowed and hardened due to the buildup of plaque, leading to cardiovascular disease 2, 3.
- While X-rays can be used to detect atherosclerosis, other imaging modalities such as ultrasound, CT scans, and MRI are more commonly used for this purpose 4.
- The detection of atherosclerosis on X-rays is not a standard practice, as X-rays are not sensitive enough to detect the early stages of the disease 4.
Imaging Modalities for Atherosclerosis
- Various imaging techniques are available to detect and quantify atherosclerosis, including contrast-enhanced ultrasound, superb microvascular imaging, and CT scans 4.
- Each imaging modality has its strengths and weaknesses, and the choice of modality depends on the specific clinical scenario and the patient's risk factors 4.
- Advanced imaging modalities, such as microvascular imaging, have shown promise in detecting vulnerable plaques and predicting cardiovascular events 4.
Clinical Significance of Atherosclerosis
- Atherosclerosis is a major risk factor for cardiovascular disease, which is the leading cause of mortality worldwide 2, 3.
- Early detection and treatment of atherosclerosis can help prevent cardiovascular events, such as heart attacks and strokes 5, 2.
- The presence of aortic valve sclerosis, which can be detected on echocardiography, has been suggested as a marker of increased cardiovascular risk 6.