What is the recommended suturing technique for excision of Xanthelesma in a patient with a possible history of lipoma and potential lipid disorders?

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Xanthelasma Excision Suturing Technique

For xanthelasma excision, perform simple excision with primary closure using fine absorbable sutures (6-0) for deep dermal layers and non-absorbable monofilament sutures (6-0 or 7-0) for skin closure, extending excision to the superficial dermis or orbicularis muscle if involved, with marker sutures for orientation if needed for complex cases. 1, 2

Surgical Approach and Depth

  • Simple excision is the primary technique for most xanthelasma cases, particularly for lesions confined to the dermis (grades I and II). 2

  • Extend excision to the superficial dermis as xanthelasma results from perivascular infiltration of foam cells within the superficial reticular dermis. 3

  • Include orbicularis oculi muscle if involved, which occurs in approximately 25% of cases—failure to excise involved muscle increases recurrence risk. 2

  • Avoid excessive depth beyond what is necessary to clear the lesion, as xanthelasma is a benign disorder and aggressive excision increases morbidity without improving outcomes. 1, 4

Suturing Technique Specifics

  • Use 6-0 absorbable sutures (such as polyglactin or poliglecaprone) for deep dermal layer closure if needed to reduce tension. 5, 6

  • Use 6-0 or 7-0 non-absorbable monofilament sutures (such as nylon or polypropylene) for skin closure to minimize scarring in this cosmetically sensitive periorbital area. 5

  • Place marker/orienting sutures if the excision involves multiple eyelids or complex anatomy to facilitate accurate assessment of any residual tissue. 7, 5

  • Ensure meticulous hemostasis before closure to prevent hematoma formation in the thin periorbital tissues. 2

Closure Options Based on Defect Size

  • Primary linear closure is appropriate for 70% of cases (grades I-II) where simple excision creates a defect that can be closed without tension. 2

  • Local flaps are required in 25% of cases (grade III) where larger defects or multiple eyelid involvement prevents primary closure. 2

  • Skin grafts are needed in 5% of cases (grade IV) with extensive involvement where local tissue is insufficient. 2

  • Secondary intention healing is an alternative option that provides good cosmetic results despite increased early morbidity, particularly useful when primary closure would create excessive tension. 4

Critical Technical Considerations

  • Complete excision of all visible xanthelasma tissue is essential, as incomplete removal is the primary cause of the 3-17% recurrence rate. 1, 2, 8

  • Avoid complex reconstruction before confirming complete excision, particularly in cases involving all four eyelids or patients with underlying hyperlipidemia, as these have higher recurrence rates. 1

  • Photograph the specimen if dealing with extensive or recurrent disease to document the extent of excision. 7

Common Pitfalls to Avoid

  • Underestimating depth of involvement: Failing to excise involved orbicularis muscle leads to recurrence—inspect the muscle layer intraoperatively. 2

  • Excessive tension on closure: This increases the 4.2% risk of scar contracture requiring secondary procedures—use local flaps or grafts when primary closure creates tension. 2

  • Ignoring lipid disorders: 50% of xanthelasma patients have dyslipidemia, and uncontrolled hyperlipidemia increases recurrence risk—coordinate with internal medicine for lipid management. 8, 3

  • Inadequate patient counseling: Patients with all four eyelids involved or underlying hyperlipidemia syndromes should be counseled about higher recurrence rates (>50%) even with complete excision. 1

References

Research

Xanthelasma: follow-up on results after surgical excision.

Plastic and reconstructive surgery, 1976

Research

Outcomes of surgical management of xanthelasma palpebrarum.

Archives of plastic surgery, 2013

Research

Xanthelasma palpebrarum - a brief review.

Clinical, cosmetic and investigational dermatology, 2018

Research

Treatment of xanthelasma by excision with secondary intention healing.

Clinical and experimental dermatology, 1996

Guideline

Excision Margins for Squamous Cell Carcinoma on the Leg

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Surgical Margins for Squamous Cell Carcinoma

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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