Abilify 1 mg Availability
No, Abilify (aripiprazole) is not available in a 1 mg tablet formulation. 1
Available Strengths
According to the FDA-approved drug label, aripiprazole tablets are manufactured and available in the following strengths only: 1
- 2 mg (lowest available dose)
- 5 mg
- 10 mg
- 15 mg
- 20 mg
- 30 mg
Clinical Implications
The 2 mg tablet represents the smallest commercially available oral dose of aripiprazole. 1 This is the appropriate starting point for patients requiring the lowest possible dose, such as:
- Elderly or frail patients who may be more sensitive to antipsychotic effects 2
- Patients requiring cautious dose titration due to tolerability concerns 3, 4
- Pediatric populations where weight-based dosing may necessitate lower starting doses 5
Dosing Considerations
The recommended starting dose for most adult patients with schizophrenia is 10-15 mg once daily, with no need for dose titration to reach the target dose. 4, 6 However, the 2 mg strength allows flexibility for:
- Gradual dose escalation in sensitive populations 2
- Dose reduction strategies when managing side effects 4
- Individualized dosing based on clinical response and tolerability 6
Steady-state plasma concentrations are achieved after 14 days of treatment, so dosage adjustments should not be made before 2 weeks of continuous therapy. 6 The mean elimination half-life is approximately 75 hours for aripiprazole, which contributes to this extended time to steady state. 4, 6