Clarification Needed: "Anti-Avidin" Is Not a Recognized Medical Treatment
I cannot provide a recommendation for "anti-avidin" or "avidin" use during pregnancy because these are not recognized pharmaceutical agents used in clinical medicine. 1
What You May Be Asking About
If you meant "antihistamines" or another allergy/asthma medication, here is guidance for asthma management during pregnancy:
Asthma Medications Safe in Pregnancy
For pregnant women with asthma, continuing asthma medications is safer than allowing uncontrolled asthma, which poses greater risks to both mother and fetus than the medications themselves. 1, 2
Short-Acting Bronchodilators (Quick Relief)
- Albuterol (salbutamol) is the preferred short-acting beta-agonist during pregnancy because it has the most extensive safety data, with reassuring evidence from 6,667 pregnant women 1, 3
- Dosing: 2-4 puffs via metered-dose inhaler as needed for symptoms 1
- For acute exacerbations: 2.5 mg via nebulizer every 20 minutes for 3 doses, then every 1-4 hours as needed 1, 2
Long-Term Controller Medications
- Inhaled corticosteroids are the preferred long-term control medication, with budesonide having the most safety data and a pregnancy category B rating 1, 2, 3
- Budesonide dosing: 200-600 mcg daily (low dose), 600-1,200 mcg daily (medium dose), >1,200 mcg daily (high dose) 4
When to Escalate Treatment
- If albuterol is needed more than twice weekly, this indicates inadequate asthma control requiring initiation or intensification of inhaled corticosteroids 1
- For severe exacerbations not controlled with bronchodilators, systemic corticosteroids (prednisone 40-60 mg daily for 3-10 days) should be added 5, 2
Risks of Uncontrolled Asthma
Uncontrolled asthma during pregnancy increases risks of: 1, 5
- Perinatal mortality
- Preeclampsia
- Preterm birth
- Low birth weight infants
Monitoring Requirements
- Monthly evaluation of asthma control and lung function throughout pregnancy 1, 2
- Asthma course changes in approximately two-thirds of pregnant women (improves in 1/3, worsens in 1/3) 1
Please Clarify Your Question
If you are asking about a different medication or treatment, please provide the correct name so I can give you accurate, evidence-based guidance.