Maximum Dose for Augmentin 600mg/5mL in Children
I cannot provide a definitive answer because the evidence provided does not contain any information about Augmentin (amoxicillin-clavulanate) dosing, and the "600mg/5mL" formulation you reference does not match standard Augmentin concentrations.
Critical Clarification Needed
The provided evidence discusses:
- Tuberculosis medications (rifampin, isoniazid) 1
- Influenza antivirals (oseltamivir, zanamivir, peramivir) 1
- Asthma medications (inhaled corticosteroids) 1
- Ondansetron (antiemetic) 2, 3
- Chlorphenamine (antihistamine) 4
None of these are Augmentin or amoxicillin-clavulanate.
Standard Augmentin Formulations (General Medical Knowledge)
Augmentin ES-600 (the likely intended formulation) contains:
- 600mg amoxicillin/42.9mg clavulanate per 5mL
- Maximum dose: 90 mg/kg/day of amoxicillin component divided twice daily
- Absolute maximum: 4000mg amoxicillin per day (regardless of weight)
Dosing Algorithm (Based on General Medical Knowledge)
For children ≥3 months with acute otitis media or sinusitis:
- Calculate weight-based dose: 45 mg/kg/dose twice daily (90 mg/kg/day total)
- Check against absolute maximum: Do not exceed 2000mg amoxicillin per dose
- Volume calculation: Dose (mg) ÷ 600mg × 5mL = volume per dose
Common pitfall: Confusing the amoxicillin component (600mg) with the total drug content—always dose based on the amoxicillin component only.
Request for Clarification
To provide evidence-based guidance, please clarify:
- Is this Augmentin ES-600 (600mg amoxicillin/5mL)?
- What is the child's weight and indication?
- Are you asking about per-dose maximum or daily maximum?