From the FDA Drug Label
Active ingredient Phenol 1.4% The product Camphphenique contains Phenol 1.4% as its active ingredient.
- The indication for this product is not explicitly stated in the provided drug label. 1
From the Research
Campho-Phenique is an over-the-counter topical medication that contains two active ingredients: camphor (10.8%) and phenol (4.7%) in a liquid or gel base, primarily indicated for the temporary relief of pain and itching associated with cold sores, fever blisters, minor cuts, scrapes, insect bites, and minor skin irritations. The product works through multiple mechanisms: camphor provides a cooling sensation that helps numb pain, while phenol acts as a local anesthetic and antiseptic that kills germs on contact. To use Campho-Phenique, apply a small amount directly to the affected area up to 3-4 times daily as needed. The medication should only be used externally and avoided around the eyes, mucous membranes, or on large areas of broken or damaged skin. Side effects are generally minimal but may include mild burning or stinging upon application. Campho-Phenique should not be used on children under 2 years of age without medical supervision, and prolonged use should be avoided as phenol can be absorbed through the skin in large amounts. Some studies have investigated the use of camphor and menthol in topical agents for pain relief and other applications 2, but the evidence is limited and more research is needed to fully understand their effects. Additionally, camphor has been shown to have potential benefits in wound healing and anti-aging 3, but these findings are based on in vitro and animal studies, and more human studies are needed to confirm these results. Overall, while Campho-Phenique can be a useful over-the-counter medication for temporary relief of pain and itching, its use should be guided by the product label and medical supervision, especially in children and individuals with sensitive skin. It is also important to note that the evidence for the use of topical agents in wound healing is limited, and more research is needed to fully understand their effects 4. In terms of wound care, preventative and treatment measures include disease-specific approaches and the use of moisture retentive dressings and adjunctive topical therapies to promote healing 5. However, the quality of the evidence for these approaches is generally low, and more research is needed to develop a greater understanding of this topic. In the context of real-life clinical medicine, it is recommended to use Campho-Phenique with caution and under medical supervision, especially in vulnerable populations, and to prioritize evidence-based wound care approaches. Some key points to consider when using Campho-Phenique include:
- Apply a small amount directly to the affected area up to 3-4 times daily as needed
- Avoid use around the eyes, mucous membranes, or on large areas of broken or damaged skin
- Use with caution in children under 2 years of age and individuals with sensitive skin
- Avoid prolonged use due to the potential for phenol absorption through the skin.