Is triamcinolone cream (Kenalog) suitable for canine use?

From the FDA Drug Label

The FDA drug label does not answer the question.

From the Research

Suitability of Triamcinolone Cream for Canine Use

• The use of triamcinolone in dogs has been studied in various contexts, including its efficacy in treating allergic pruritus 1 and mast cell tumors 2.
• A multiple-center study found that triamcinolone topical solution was effective in reducing clinical signs of pruritic inflammatory skin diseases in dogs, with minor adverse effects reported in 12% of treated dogs 1.
• Intralesional triamcinolone administration has been shown to be well tolerated and effective for treatment of nonresectable mast cell tumors in dogs, with a response rate of 67% 2.
• However, long-term administration of triamcinolone acetonide in dogs has been associated with adverse effects such as polyuria, hyperphagia, and muscle weakness 3.
• The pharmacokinetic and pharmacodynamic mechanisms of intramuscular triamcinolone acetonide are not fully understood, but its unique binding mechanisms and low solubility in blood may contribute to its long-term effects on dermatologic disease 4.

Key Findings

• Triamcinolone can be effective in treating allergic pruritus and mast cell tumors in dogs 1, 2.
• Adverse effects of triamcinolone use in dogs can include polyuria, hyperphagia, and muscle weakness 3.
• The pharmacokinetics of intramuscular triamcinolone acetonide are complex and not fully understood 4.