From the Guidelines
Brilinta (ticagrelor) is not known to raise TSH (thyroid-stimulating hormone) levels. The provided evidence does not support a link between Brilinta and elevated TSH levels. The studies referenced 1 discuss the management of hepatitis C and the adverse effects of antiviral therapy, but do not mention Brilinta or its effects on thyroid function.
- Brilinta is an antiplatelet medication primarily used to prevent blood clots in patients with acute coronary syndrome or history of heart attack.
- It works by inhibiting platelet aggregation and has no direct effect on thyroid function or TSH regulation.
- If you're taking Brilinta and experiencing symptoms of thyroid dysfunction (such as fatigue, weight changes, or sensitivity to temperature), or if you've noticed elevated TSH levels on blood tests, these effects are likely unrelated to Brilinta use.
- Other medications like amiodarone, lithium, or certain immunotherapies are more commonly associated with thyroid function changes.
- If you're concerned about your TSH levels while taking Brilinta, consult your healthcare provider for proper evaluation, as thyroid abnormalities may require separate assessment and treatment while continuing your necessary antiplatelet therapy.
From the Research
Effects of Brilinta on TSH Levels
- There is no direct evidence in the provided studies that suggests Brilinta (ticagrelor) can raise Thyroid-Stimulating Hormone (TSH) levels 2, 3, 4, 5, 6.
- The studies primarily focus on the pharmacokinetics, efficacy, and safety of ticagrelor in patients with acute coronary syndromes, comparing it to other antiplatelet agents like clopidogrel and prasugrel.
- None of the studies mention the effect of ticagrelor on thyroid function or TSH levels, indicating a lack of research in this specific area 2, 3, 4, 5, 6.
Related Research
- The provided studies discuss the pharmacological properties and clinical applications of ticagrelor, including its use in patients with acute coronary syndromes and its comparison to other antiplatelet agents 2, 3, 5, 6.
- One study reports a case of ticagrelor-induced thrombotic thrombocytopenic purpura, highlighting the importance of monitoring for rare but potentially severe side effects 4.
- However, none of these studies investigate the potential effects of ticagrelor on thyroid function or TSH levels, leaving this question unanswered 2, 3, 4, 5, 6.