From the Guidelines
Black mold exposure can potentially elevate inflammatory markers like C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR/sed rate) in some individuals. When people are exposed to black mold (Stachybotrys chartarum) and develop an inflammatory response to the mold spores or mycotoxins, their body may produce these markers as part of the immune system's reaction. This is particularly likely in people who develop hypersensitivity pneumonitis, allergic bronchopulmonary aspergillosis, or other inflammatory conditions in response to mold exposure. However, elevated CRP and sed rate are non-specific indicators of inflammation that can be caused by many different conditions, including infections, autoimmune disorders, and other environmental exposures.
Key Considerations
- The current evidence does not provide a clear link between black mold exposure and elevated CRP and sed rate, as noted in the studies from 1 and 1.
- The US Environmental Protection Agency (EPA) and the CDC offer practical guidelines for mold control and cleanup in the home setting, which can help reduce exposure to black mold and potentially decrease the risk of elevated inflammatory markers.
- If you have elevated inflammatory markers and suspect black mold exposure, it's essential to have both a medical evaluation and an environmental assessment of your home or workplace.
Treatment and Prevention
- Treatment typically involves removing the source of mold exposure and addressing any resulting health conditions with appropriate medications, which might include antihistamines, corticosteroids, or other treatments depending on your specific symptoms and condition.
- Prompt remediation of water damage in homes and other buildings is crucial to prevent mold growth and reduce the risk of exposure, as recommended by the CDC and EPA 1.
From the Research
Inflammatory Markers and Black Mold Exposure
- There is no direct evidence to suggest that black mold exposure elevates CRP and sed rate 2, 3.
- However, studies have shown that inflammatory biomarkers such as CRP can be influenced by various factors, including glucocorticoid treatment 4, 5.
- CRP levels have been found to be reduced in patients treated with prednisone, a glucocorticoid, in community-acquired pneumonia 4.
- In patients with bronchiectasis, elevated CRP levels have been associated with a greater risk of future severe exacerbations 6.
- The relationship between black mold exposure and inflammatory markers is not well established, and more research is needed to determine any potential effects 3.
Black Mold and Human Health
- Black mold is a type of fungus that can cause disease in humans, particularly in immunocompromised individuals 2, 3.
- Exposure to black mold has been linked to various health problems, including allergies, asthma, and hypersensitivity diseases 3.
- However, there is no scientific evidence to support the existence of "toxic mold syndrome" or "toxic black mold" as a distinct medical condition 3.