From the FDA Drug Label
Apply a thin layer of VANIQA (eflornithine hydrochloride) Cream, 13.9% to affected areas of the face and adjacent involved areas under the chin and rub in thoroughly. Do not wash treated area for at least 4 hours. Use twice daily at least 8 hours apart or as directed by a physician. Apply a thin layer of VANIQA to the affected areas of the face and adjacent involved areas under the chin and rub in thoroughly. You should not wash the treatment areas for at least 4 hours after application of VANIQA.
To correctly apply eflornithine topical cream for hirsutism:
- Apply a thin layer of the cream to the affected areas of the face and adjacent involved areas under the chin.
- Rub in thoroughly to ensure the cream is evenly distributed.
- Do not wash the treated area for at least 4 hours after application.
- Use twice daily, with an interval of at least 8 hours between applications, or as directed by a physician 1.
- Continue to use hair removal techniques as needed in conjunction with VANIQA 1.
From the Research
To correctly apply eflornithine topical cream for hirsutism, wash and dry the affected area thoroughly, then apply a thin layer of the cream (brand name Vaniqa) to the unwanted facial hair areas twice daily, at least 8 hours apart, as supported by the most recent and highest quality study available 2.
Application Instructions
- Use only a pea-sized amount for each application, spreading it evenly and rubbing it in thoroughly until no residue remains visible.
- Do not wash the treated area for at least 4 hours after application.
- Continue regular hair removal methods (such as shaving or plucking) as needed, but avoid applying the cream immediately after these procedures—wait at least 5 minutes after shaving or 8 hours after other hair removal methods.
Expected Outcomes and Side Effects
- Results typically appear within 4-8 weeks of consistent use, with optimal results seen after 6 months, as noted in the study 2.
- Eflornithine works by inhibiting the enzyme ornithine decarboxylase, which slows down hair growth rather than removing hair.
- If no improvement is seen after 6 months, discontinue use and consult your healthcare provider.
- Common side effects may include temporary stinging, burning, or redness at the application site.
Considerations for Treatment
- The treatment of hirsutism often requires a multidisciplinary approach, and a variety of physical or pharmacologic modalities can be employed, as discussed in the study 3.
- Physical modalities and oral contraceptive pills (OCPs) remain first-line treatments, with evidence supporting the use of electrolysis for permanent hair removal in localized areas and lasers for permanent hair reduction, as outlined in the study 2.
- Topical eflornithine can be used as monotherapy for mild hirsutism and as an adjunct therapy with lasers or pharmacotherapy in more severe cases, as recommended in the study 2.