Can a breastfeeding mother take DayQuil (dextromethorphan and acetaminophen)?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: January 9, 2026View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Can a Breastfeeding Mother Take DayQuil?

Yes, a breastfeeding mother can take DayQuil, as both of its active ingredients—acetaminophen and dextromethorphan—are considered compatible with breastfeeding when used at recommended doses for short durations. 1, 2, 3

Acetaminophen Safety

  • Acetaminophen (paracetamol) is safe during breastfeeding, with the amount transferred to breast milk being significantly less than the pediatric therapeutic dose. 1
  • The Association of Anaesthetists confirms that despite wide variation in breast milk concentrations, the infant's exposure remains well below therapeutic levels. 1
  • The FDA drug label advises consulting a health professional before use during breastfeeding, but this is standard precautionary language rather than a contraindication. 4
  • Multiple sources confirm acetaminophen as a preferred first-line analgesic for breastfeeding women. 2, 5

Dextromethorphan (Cough Suppressant) Safety

  • Dextromethorphan is acceptable for short-term use during breastfeeding, though specific human data are limited. 3
  • The American Academy of Pediatrics considers codeine (a related cough suppressant) compatible with breastfeeding, and dextromethorphan has an even more favorable profile with less sedation risk. 3
  • Studies on cough and cold preparations conclude that low levels reach breastfed infants when mothers take these medications. 3

Practical Recommendations

  • Take DayQuil immediately after breastfeeding to minimize infant exposure, as this allows maximum time for drug clearance before the next feeding. 2, 5, 3
  • Use the lowest effective dose for the shortest duration necessary to manage cold symptoms. 1, 5, 3
  • Monitor your infant for unusual drowsiness, irritability, or poor feeding, though these effects are unlikely with DayQuil's components. 3

Important Caveats

  • Avoid DayQuil formulations containing alcohol, as many liquid cold products contain ethanol. 3
  • Avoid combination products with aspirin, which should be used with caution during breastfeeding due to potential adverse effects in infants. 3
  • Decongestants (like phenylephrine or pseudoephedrine, if present in certain DayQuil formulations) may theoretically reduce milk supply in some women, though pseudoephedrine is considered compatible with breastfeeding. 3
  • If symptoms persist beyond a few days or worsen, consult a healthcare provider rather than continuing self-medication. 2

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Medication Safety in Breastfeeding.

American family physician, 2022

Research

Use of cough and cold preparations during breastfeeding.

Journal of human lactation : official journal of International Lactation Consultant Association, 1999

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.