What causes hyperhidrosis in adolescents?

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Last updated: April 11, 2025View editorial policy

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Differential Diagnosis for Excessive Sweating in Adolescents

Single Most Likely Diagnosis

  • Hyperhidrosis: This is a common condition characterized by excessive sweating, often affecting the palms, soles, and armpits. It can be primary (idiopathic) or secondary to other medical conditions. In adolescents, primary hyperhidrosis is the most likely cause, often triggered by emotional stress, heat, or exercise.

Other Likely Diagnoses

  • Anxiety or Stress: Adolescents may experience excessive sweating due to anxiety or stress, which can be related to school, social, or family pressures.
  • Hypothyroidism: Although less common, hypothyroidism can cause excessive sweating, among other symptoms like weight gain, fatigue, and cold intolerance.
  • Precocious Puberty: Early onset of puberty can lead to excessive sweating due to hormonal changes.

Do Not Miss Diagnoses

  • Pheochromocytoma: A rare tumor of the adrenal gland that can cause excessive sweating, palpitations, and hypertension. Although unlikely, it's crucial to rule out this condition due to its potential severity.
  • Thyroid Storm: A life-threatening condition caused by excessive thyroid hormones, which can lead to excessive sweating, tachycardia, and fever.
  • Infectious Diseases: Certain infections like tuberculosis, endocarditis, or osteomyelitis can cause excessive sweating, especially at night.

Rare Diagnoses

  • Frey's Syndrome: A rare condition characterized by excessive sweating and flushing of the face, often triggered by eating certain foods.
  • Riley-Day Syndrome: A rare genetic disorder that affects the development of the nervous system, causing excessive sweating, among other symptoms.
  • Carcinoid Syndrome: A rare condition caused by a neuroendocrine tumor, which can lead to excessive sweating, flushing, and diarrhea.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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