What is the recommended tetanus (lockjaw) vaccination protocol after a dog bite?

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Last updated: April 11, 2025View editorial policy

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From the Guidelines

After a dog bite, you should get a tetanus vaccine if your last tetanus shot was more than 5 years ago or if you're unsure of your vaccination status. The standard tetanus vaccine is Tdap (tetanus, diphtheria, and pertussis) or Td (tetanus and diphtheria) depending on your vaccination history, as recommended by the Advisory Committee on Immunization Practices (ACIP) 1. For contaminated wounds like animal bites, the 5-year guideline applies, and a tetanus booster is recommended if your last dose was more than 5 years ago 1. Dog bites can introduce bacteria deep into tissues, creating an ideal environment for Clostridium tetani, the bacterium that causes tetanus. This bacterium produces a toxin that causes painful muscle contractions and can be life-threatening.

Key Considerations

  • The decision to administer a tetanus vaccine should be based on the primary vaccination history for tetanus, as outlined in Table 6 of the ACIP recommendations 1.
  • If you've never been vaccinated against tetanus, you may also need tetanus immune globulin (TIG) along with the vaccine to provide immediate protection 1.
  • In addition to the tetanus vaccine, dog bite wounds should be thoroughly cleaned with soap and water, and you should seek medical attention to assess the need for antibiotics to prevent infection.

Vaccination Guidelines

  • Tdap is preferred over Td if you're aged 11 years or older and have not previously received Tdap 1.
  • If you're pregnant, Tdap should be used if a tetanus toxoid–containing vaccine is indicated 1.
  • If you have a history of an Arthus reaction following a previous dose of a tetanus toxoid–containing vaccine, you should not receive a tetanus toxoid–containing vaccine until more than 10 years after the most recent dose 1.

From the FDA Drug Label

For active tetanus immunization in wound management of patients 7 years of age and older, a preparation containing tetanus and diphtheria toxoids is preferred instead of single-antigen tetanus toxoid to enhance diphtheria protection. The need for active immunization with a tetanus toxoid-containing preparation, with or without passive immunization with Tetanus Immune Globulin (TIG) (Human) depends on both the condition of the wound and the patient's vaccination history. Table 1: Guide for use of Tetanus and Diphtheria Toxoids Adsorbed (Td) for Tetanus Prophylaxis in Routine Wound Management in Persons 7 Years of Age and Older History of Adsorbed Tetanus Toxoid (Doses)Clean, Minor WoundsAll Other Wounds* TdTIGTdTIG

  • Such as, but not limited to, wounds contaminated with dirt, puncture wounds and traumatic wounds † If only three doses of fluid tetanus toxoid have been received, then a fourth dose of toxoid, preferably an adsorbed toxoid should be given. ‡ Yes, if >10 years since last dose. § Yes, if >5 years since last dose.

The tetanus vaccine may be indicated after a dog bite, depending on the condition of the wound and the patient's vaccination history.

  • For clean, minor wounds, tetanus vaccine is not necessary if the patient has had three or more doses of tetanus toxoid and the last dose was less than 10 years ago.
  • For all other wounds (e.g. contaminated with dirt, puncture wounds, traumatic wounds), tetanus vaccine is necessary if the patient has had less than three doses of tetanus toxoid or if the last dose was more than 5 years ago. It is recommended to consult the Table 1 guide for specific guidance on tetanus prophylaxis in wound management 2.

From the Research

Tetanus Vaccine Administration

  • The provided studies do not directly address the administration of tetanus vaccine after a dog bite.
  • However, one study 3 discusses the safety of immunizing with tetanus-diphtheria-acellular pertussis vaccine (Tdap) less than 2 years following previous tetanus vaccination, which may be relevant to understanding tetanus vaccine administration in general.

Relevance to Dog Bites

  • Neither of the studies 3, 4 specifically addresses the topic of tetanus vaccine administration after a dog bite.
  • Study 4 appears to be unrelated to vaccine administration, as it discusses the effects of hemorrhagic shock, hypoxemia, and anoxia on energy metabolism.

Available Information

  • There is no direct evidence provided to assist in answering the question about tetanus vaccine administration after a dog bite.
  • Further research or consultation with medical professionals may be necessary to determine the appropriate course of action for tetanus vaccine administration after a dog bite.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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