What is the cause of petechiae with facial itchy rash (pruritus)?

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Differential Diagnosis for Petechiae, Facial Itchy Rash

  • Single Most Likely Diagnosis
    • Atopic Dermatitis (Eczema): This condition is characterized by itchy, inflamed skin and can sometimes present with petechiae due to scratching. The facial involvement and itchiness are common in atopic dermatitis.
  • Other Likely Diagnoses
    • Contact Dermatitis: An allergic or irritant reaction to substances like cosmetics, soaps, or metals can cause an itchy rash on the face, potentially accompanied by petechiae if the skin is scratched.
    • Urticaria: Hives can appear anywhere on the body, including the face, and are often itchy. While petechiae are not a primary feature, severe scratching can lead to their appearance.
    • Insect Bites: Certain insect bites can cause itchy rashes and, in some cases, petechiae, especially if there's an allergic reaction or if the bites become infected.
  • Do Not Miss Diagnoses
    • Meningococcemia: This is a life-threatening infection that can cause a rash, which may initially appear as petechiae. Although it's less common, the severity of the condition necessitates its consideration, especially if accompanied by symptoms like fever, headache, or stiff neck.
    • Thrombocytopenia: Low platelet count can lead to petechiae. If the patient also has an itchy rash, it could be due to a separate condition or a manifestation of the underlying cause of thrombocytopenia, such as an autoimmune disorder.
    • Vasculitis: Certain types of vasculitis, like leukocytoclastic vasculitis, can present with a rash and petechiae. The condition can be serious and requires prompt diagnosis and treatment.
  • Rare Diagnoses
    • Erythema Multiforme: A skin condition characterized by target lesions, which can sometimes appear on the face and may be accompanied by petechiae in severe cases.
    • Sweet Syndrome: Also known as acute febrile neutrophilic dermatosis, it can cause a rash and may include petechiae, though it's more commonly associated with fever and neutrophilia.
    • Amyloidosis: In rare cases, amyloidosis can cause skin lesions, including petechiae, though this would typically be part of a broader systemic disease presentation.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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