Treatment of Bell's Palsy
Prescribe oral corticosteroids within 72 hours of symptom onset—prednisolone 50 mg daily for 10 days or prednisone 60 mg daily for 5 days followed by a 5-day taper—as this is the only proven effective treatment that significantly improves facial nerve recovery. 1
Immediate Management (Within 72 Hours)
Corticosteroid Therapy (First-Line, Mandatory)
- Start oral corticosteroids immediately for all patients 16 years and older with Bell's palsy presenting within 72 hours of symptom onset 1
- Use either:
- Evidence demonstrates 83% recovery at 3 months with prednisolone versus 63.6% with placebo, and 94.4% recovery at 9 months versus 81.6% with placebo 1
- Do not initiate corticosteroids beyond 72 hours—there is no evidence of benefit after this window 1
Antiviral Therapy (Optional, Minimal Benefit)
- Never prescribe antiviral monotherapy—it is completely ineffective 1, 2
- May offer combination therapy with valacyclovir 1 g orally three times daily for 7 days PLUS corticosteroids within 72 hours 1, 2
- Alternative: acyclovir 400 mg orally five times daily for 10 days PLUS corticosteroids 1
- The added benefit is minimal (96.5% complete recovery with combination versus 89.7% with steroids alone), but risks are low 1
Eye Protection (Critical, Mandatory)
- Implement aggressive eye protection immediately for all patients with impaired eye closure to prevent permanent corneal damage 1
- Daytime regimen:
- Nighttime regimen:
- Refer urgently to ophthalmology if complete inability to close eye or signs of corneal exposure/damage 1
Special Populations
Pediatric Patients
- Children have better prognosis with up to 90% spontaneous recovery rates 2
- Evidence for corticosteroid benefit in children is inconclusive 1
- May consider prednisolone 1 mg/kg/day (maximum 50-60 mg) for 5 days followed by 5-day taper for severe/complete paralysis, but only with substantial caregiver participation in shared decision-making 1
- Clearly inform families that most children recover completely without treatment and steroid benefit remains unproven in pediatrics 1
Pregnant Women
- Treat with oral corticosteroids within 72 hours using individualized risk-benefit assessment 1
- Pregnancy is a risk factor for Bell's palsy, but corticosteroids can be used safely 2
- Eye protection measures are essential and safe in pregnancy 1
Diagnostic Considerations
Confirm Diagnosis (Exclusion of Other Causes)
- Bell's palsy is a diagnosis of exclusion—no identifiable cause for acute unilateral facial nerve paresis/paralysis with onset <72 hours 1, 3
- Must involve forehead weakness (distinguishes from stroke, which spares forehead) 1, 3
- Exclude: trauma, infection (Lyme disease, herpes zoster), tumor, stroke, sarcoidosis, Guillain-Barré syndrome 3
- Do NOT order routine laboratory testing or imaging for typical presentations 1, 3
Red Flags Requiring Imaging (MRI with and without contrast)
- Recurrent paralysis on same side 1
- Isolated branch paralysis 1
- Other cranial nerve involvement 1, 3
- Bilateral facial weakness 3
- Progressive weakness beyond 3 weeks 1
- No recovery after 3 months 1
Electrodiagnostic Testing
- May offer to patients with complete facial paralysis (not incomplete) 1
- Most reliable when performed 3-14 days post-onset 1
10% nerve response amplitude compared to unaffected side indicates excellent prognosis 1
- <10% function carries up to 50% risk of incomplete recovery 1
Follow-Up and Reassessment
Mandatory Follow-Up Timeline
- Initial visit within 72 hours for treatment initiation and eye care education 1
- Early follow-up at 1-2 weeks to assess recovery trajectory and reinforce eye protection 1
- Mandatory reassessment at 3 months for all patients with incomplete recovery 1
Urgent Reassessment Triggers (At Any Time)
- New or worsening neurologic findings (suggests stroke, tumor, or CNS pathology) 1, 3
- Development of ocular symptoms (requires urgent ophthalmology referral) 1
- Progressive weakness beyond 3 weeks 1
Specialist Referral Indications
- Incomplete facial recovery at 3 months—refer to facial nerve specialist or facial plastic surgeon for reconstructive options 1
- Persistent eye closure problems—refer to ophthalmology 1
- Consider tarsorrhaphy (partial eyelid closure) or eyelid weight implantation for severe persistent lagophthalmos 1
Prognosis
Expected Recovery Rates
- Patients with incomplete paralysis: up to 94% complete recovery 1, 2
- Patients with complete paralysis: approximately 70% complete recovery within 6 months 1
- Most patients begin showing recovery within 2-3 weeks 1
- Complete recovery typically occurs within 3-4 months 1
- 30% may experience permanent facial weakness with muscle contractures 1
Therapies NOT Recommended
- Physical therapy: no proven benefit over spontaneous recovery 1, 3
- Acupuncture: poor quality evidence, indeterminate benefit-harm ratio 1, 3
- Surgical decompression: rarely indicated except in specialized centers for specific cases 1
- Antiviral monotherapy: completely ineffective, never prescribe alone 1, 2
Common Pitfalls to Avoid
- Delaying corticosteroid treatment beyond 72 hours eliminates effectiveness 1
- Prescribing antivirals alone without corticosteroids (completely ineffective) 1, 2
- Inadequate eye protection leading to permanent corneal damage 1
- Failing to refer at 3 months with incomplete recovery, delaying reconstructive options 1
- Missing red flags suggesting alternative diagnoses (bilateral weakness, other cranial nerve involvement, progressive symptoms) 1, 3
- Overlooking psychological impact in patients with persistent facial asymmetry 1