Timing of Meningococcal Vaccine After Quadracel and Varicella
You can administer the meningococcal conjugate vaccine (MenACWY) immediately on the same day as Quadracel and varicella vaccines, or at any time thereafter without any required waiting period.
No Waiting Period Required
There is no minimum interval required between varicella vaccine and meningococcal conjugate vaccines - these can be given simultaneously at different anatomic sites or at any interval. 1
The key consideration is the relationship between DTaP-containing vaccines (like Quadracel) and MenACWY-D specifically, not the timing after administration. 1
Important Distinction Based on Vaccine Product
If Using MenACWY-D (Menactra):
- MenACWY-D should ideally be given either before or at the same time as DTaP to avoid interference with the immune response to the meningococcal vaccine. 1
- Since Quadracel (which contains DTaP) has already been administered, this timing consideration has passed.
- You can still proceed with MenACWY-D administration - the recommendation is about optimal timing, and the vaccine remains safe and effective when given after DTaP. 1
If Using MenACWY-CRM (Menveo) or MenACWY-TT (MenQuadfi):
- These formulations have no timing restrictions related to DTaP administration and can be given at any time. 1, 2
- MenACWY-CRM or MenACWY-TT would be the preferred choice in this scenario since Quadracel has already been given. 2
Practical Recommendation
- Administer MenACWY-CRM (Menveo) or MenACWY-TT (MenQuadfi) at the child's next visit without any required waiting period. 2
- If only MenACWY-D is available, it can still be administered safely - the timing recommendation is for optimization, not a contraindication. 1
- All meningococcal conjugate vaccines can be coadministered with other routine vaccines at different anatomic sites. 1, 2