What are the discharge instructions for a patient with a laceration repaired with tissue adhesive (glue)?

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Discharge Instructions for Laceration Repaired with Tissue Adhesive

Keep the wound dry for the first 24 hours, then gentle washing is acceptable, but avoid soaking, scrubbing, or applying ointments directly to the adhesive as this will cause it to dissolve prematurely. 1, 2

Wound Care

  • Do not apply antibiotic ointment, petroleum jelly, or any topical products directly on the tissue adhesive, as these will break down the glue and cause wound separation 3
  • The adhesive will naturally peel off in 5-10 days as the wound heals underneath—do not pick at it or try to remove it 4, 3
  • After 24 hours, you may gently wash around the wound with soap and water, but avoid direct scrubbing of the adhesive 2
  • Pat the area dry; do not rub 2
  • No swimming, bathing, or prolonged water exposure until the adhesive has completely fallen off 3

Pain Management

  • Use over-the-counter acetaminophen or ibuprofen as needed for pain 5, 6
  • Apply ice packs wrapped in a towel for 15-20 minutes at a time during the first 24-48 hours to reduce pain and swelling 5, 6

Activity Restrictions

  • Avoid activities that create tension or stretching across the wound site, as tissue adhesive works best in low-tension areas 4, 3
  • If the laceration is near a joint, minimize movement of that area for the first few days 7
  • Avoid heavy lifting or strenuous exercise until the adhesive has fallen off and the wound appears well-healed 8

Signs of Infection—Seek Medical Attention If You Develop:

  • Increasing pain, redness, or swelling around the wound 6
  • Purulent (pus) discharge or foul odor 6
  • Fever over 100.4°F (38°C) 8
  • Red streaking extending from the wound 6
  • Wound separation or edges pulling apart 1

Tetanus Immunization

  • Ensure your tetanus vaccination is up to date; if your last tetanus shot was more than 5 years ago (for dirty wounds) or 10 years ago (for clean wounds), you may need a booster 4, 8

Follow-Up

  • No suture removal is needed since tissue adhesive dissolves on its own 3
  • Return for evaluation if the wound shows any signs of infection or if the adhesive falls off prematurely before the wound edges are sealed 1, 4
  • The wound will continue to strengthen over several weeks even after the adhesive has fallen off 2

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Laceration Repair: A Practical Approach.

American family physician, 2017

Research

Essentials of skin laceration repair.

American family physician, 2008

Research

[Wound management for cuts and lacerations].

Medizinische Monatsschrift fur Pharmazeuten, 2015

Guideline

Minor Laceration Care

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Treatment for Scalp Laceration

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Layered closure of lacerations.

Postgraduate medicine, 1988

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Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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